| M.A.N.T.I.S. | Fox | 1994–1995 | 1 | 22 | Science fiction |
| M*A*S*H | CBS | 1972–1983 | 11 | 256 | Comedy-drama |
| M.A.S.K.Animated series | CBS, TF1 | 1985–1986 | 2 | 75 | Comedy |
| M.I.A. | Paramount+ | 2026–on air | 1 | 9 | Gangster |
| M.O.D.O.K.Animated series | Hulu | 2021 | 1 | 10 | — |
| M Squad | NBC | 1957–1960 | 3 | 117 | Crime |
| M.Y.O.B. | NBC | 2000 | 1 | 8 | Comedy |
| MacGruber | Peacock | 2021–on air | 1 | 8 | — |
| MacGruder and Loud | ABC | 1985 | 1 | 14 | Drama |
| MacGyver | ABC | 1985–1992 | 7 | 139 | Action |
| MacGyver | CBS | 2016–2021 | 5 | 94 | Adventure |
| Machines of Malice | Discovery Channel | 2008 | — | 6 | Documentary |
| Mack & Myer for Hire | Syndication | 1963–1964 | 1 | — | Sitcom |
| Mackenzie's Raiders | Syndication | 1958–1959 | 1 | 39 | Western |
| MadAnimated series | Cartoon Network | 2010–2013 | 4 | 103 | Comedy |
| Mad About You | NBC | 1992–1999 | 7 | 164 | Sitcom |
| Mad Dogs | Prime Video | 2015–2016 | 1 | 10 | Thriller |
| Mad Fashion | Bravo | 2011 | 1 | 10 | Reality |
| Mad Jack the PirateAnimated series | Fox, Fox Kids | 1998–1999 | 1 | 13 | Comedy |
| Mad Love | CBS | 2011 | 1 | 13 | Sitcom |
| Mad Mad House | Syfy | 2004 | 1 | 10 | Reality |
| Mad Men | AMC | 2007–2015 | 7 | 92 | Drama |
| Mad TV | Fox | 1995–2009 | 15 | 321 | Sketch comedy |
| Madagascar: A Little WildAnimated series | Peacock, Hulu | 2020–2022 | 7 | 45 | Animation |
| Madam Secretary | CBS | 2014–2019 | 6 | 120 | Drama |
| Madame's Place | Syndication | 1982–1983 | 1 | 150 | Sitcom |
| Madden Nation | ESPN2 | 2005 | 4 | 32 | American football video game |
| Made | MTV2, MTV | 2002–2014 | 13 | 280 | Reality |
| Made for Love | HBO Max | 2021–2022 | 2 | 16 | Black comedy |
| Made in America | Travel Channel | 2004–2008 | 5 | 97 | Documentary |
| Made in Jersey | CBS | 2012 | 1 | 8 | Legal drama |
| MadelineAnimated series | Freeform, ICI Radio-Canada Télé | 1993–2001 | 3 | 59 | Children's |
| MadHouse | History | 2010 | 1 | 13 | Reality |
| Madiba | BET | 2017 | — | 3 | — |
| Madigan Men | ABC | 2000 | 1 | 12 | Sitcom |
| The Madison | Paramount+ | 2026–on air | 1 | 6 | Family drama |
| Madman of the People | NBC | 1994–1995 | 1 | 16 | Sitcom |
| Madoff | ABC | 2016 | 1 | 4 | — |
| Madoff: The Monster of Wall Street | Netflix | 2023 | 1 | 4 | Documentary |
| Mafia Killers with Colin McLaren | Reelz | 2018 | 1 | 6 | — |
| Maggie | Lifetime | 1998–1999 | 1 | 22 | Sitcom |
| Maggie | Hulu | 2022–on air | 1 | 13 | Comedy |
| Maggie Briggs | CBS | 1984 | 1 | 6 | Sitcom |
| Maggie Winters | CBS | 1998–1999 | 1 | 18 | Sitcom |
| Magic City | Starz | 2012–2013 | 2 | 16 | Drama |
| The Magic Garden | WPIX | 1972–1984 | 12 | 52 | — |
| The Magic Hour | Syndication | 1998 | 1 | 12 | Talk show |
| The Magic Land of Allakazam | ABC, CBS | 1960–1964 | — | 98 | — |
| The Magic School BusAnimated series | PBS, Qubo | 1994–1997 | 4 | 52 | Children's |
| Magical Girl Friendship SquadAnimated series | Syfy | 2020 | — | — | Comedy |
| Magical Girl Friendship Squad: Origins | Syfy | 2020–on air | — | — | Adult animation |
| The Magical Legend of the LeprechaunsMiniseries | NBC, Telecinco | 1999 | 1 | 2 | Fantasy |
| The Magician | CBS | 1973–1974 | 1 | 21 | Action |
| The Magicians | Syfy | 2015–2020 | 5 | 65 | Fantasy |
| Magicland | WMC-TV | 1966–1989 | — | — | — |
| The Magilla Gorilla ShowAnimated series | Syndication | 1964–1966 | — | 31 | — |
| The Magnificent Seven | CBS | 1998–2000 | 2 | 22 | Western |
| Magnum, P.I. | CBS | 1980–1988 | 8 | 162 | Action |
| Magnum, P.I. | CBS, NBC | 2018–2024 | 5 | 96 | Drama |
| The Maharaja's DaughterMiniseries | Canale 5 | 1995 | — | 3 | — |
| Maid | Netflix | 2021–on air | — | 10 | Drama |
| Maid in Manhattan | NBC | 2011–2012 | 1 | 163 | Romantic comedy |
| The Main Event | NBC | 1988–1991 | — | 5 | Professional wrestling |
| MaisyAnimated series | CITV | 1999–2000 | 1 | 28 | — |
| Major Crimes | TNT | 2012–2018 | 6 | 105 | Drama |
| Major Dad | CBS | 1989–1993 | 4 | 96 | Sitcom |
| Major Lazer | FXX | 2015 | 1 | 11 | Cartoon |
| Majors & Minors | Discovery Family | 2011–2012 | 1 | 15 | — |
| Make a Wish | ABC | 1971–1976 | 5 | — | — |
| Make It or Break It | Freeform | 2009–2012 | 3 | 48 | Youth |
| Make It Pop | Nickelodeon, YTV | 2015–2016 | 2 | 26 | Sitcom |
| Make Me a Millionaire | Syndication | 2009–2010 | 2 | 82 | — |
| Make Me a Millionaire Inventor | CNBC | 2015–2016 | 1 | 6 | — |
| Make Me a Supermodel | Bravo | 2008–2009 | 2 | 30 | Reality |
| Make Me Laugh | ABC | 1958–1998 | — | — | Panel game |
| Make Room for Daddy | ABC | 1953–1964 | 11 | 343 | Sitcom |
| Make the Connection | NBC | 1955 | — | 13 | — |
| Make the Grade | Nickelodeon | 1989–1990 | 3 | 160 | — |
| Make Way for NoddyAnimated series | PBS, PBS Kids | 2002–2007 | 2 | 100 | Comedy |
| Make Your Own Kind of Music | NBC | 1971 | — | 8 | — |
| Makin' It | ABC | 1979 | 1 | 9 | Sitcom |
| Making a Murderer | Netflix | 2015–2018 | 2 | 20 | Documentary |
| Making FiendsAnimated series | Nicktoons | 2008 | 1 | 6 | — |
| Making History | Fox | 2017 | 1 | 9 | Comedy |
| Making It | NBC | 2018–2021 | 1 | 6 | Reality |
| The Making of the Mob | AMC | 2015–2016 | 2 | 16 | Documentary |
| Making the Band | ABC, MTV | 2000–2009 | 12 | 142 | Reality |
| Making the Grade | CBS | 1982 | 1 | 6 | Sitcom |
| Making the Video | MTV | 1999 | 14 | 240 | — |
| Malcolm & Eddie | UPN | 1996–2000 | 4 | 89 | Sitcom |
| Malcolm in the Middle | Fox | 2000–2006 | 7 | 151 | Coming-of-age |
| Malcolm in the Middle: Life's Still Unfair | Disney+ | 2026–on air | — | 4 | Black comedy |
| Malibu, CA | Syndication | 1998–2000 | 2 | 52 | Teen sitcom |
| Malibu Country | ABC | 2012–2013 | 1 | 18 | Sitcom |
| Malibu Rescue | Netflix | 2019–2020 | 1 | 8 | Comedy |
| Malibu Shores | NBC | 1996 | 1 | 10 | Teen drama |
| Malibu U | ABC | 1967 | 1 | 7 | Variety show |
| Mall Cops: Mall of America | TLC | 2010 | 1 | 12 | Reality |
| Malverde: El Santo Patrón | Telemundo | 2021–2022 | 1 | 80 | Telenovela |
| Mama | CBS | 1949–1957 | 8 | 336 | Sitcom |
| Mama Drama | VH1 | 2010–2012 | 1 | 10 | Reality |
| Mama Malone | CBS | 1984 | 1 | 13 | Sitcom |
| Mama Rosa | ABC | 1950 | 1 | 12 | Sitcom |
| Mama's Boy | NBC | 1987–1988 | 1 | 7 | Sitcom |
| Mama's Family | NBC | 1983–1990 | 6 | 130 | Sitcom |
| Man Against Crime | CBS | 1949–1954 | 5 | 122 | Police procedural |
| The Man and the Challenge | NBC | 1959–1960 | 1 | 36 | Science fiction |
| The Man and the City | ABC | 1971–1972 | 1 | 15 | — |
| The Man Behind the Badge | CBS | 1953–1955 | 2 | 90 | Police procedural |
| A Man Called Hawk | ABC | 1989 | 1 | 13 | Drama |
| A Man Called Shenandoah | ABC | 1965–1966 | 1 | 34 | Western |
| A Man Called Sloane | NBC | 1979 | 1 | 12 | — |
| Man Finds Food | 7mate | 2014–2017 | 1 | 15 | — |
| Man Fire Food | Cooking Channel | 2012 | 9 | 119 | — |
| Man from Atlantis | NBC | 1977–1978 | 1 | 17 | Science fiction |
| The Man from Blackhawk | ABC | 1959–1960 | 1 | 37 | Western |
| The Man from U.N.C.L.E. | NBC | 1964–1968 | 4 | 105 | Crime |
| A Man in Full | Netflix | 2024 | 1 | 6 | Drama |
| The Man in the Family | ABC | 1991 | 1 | 7 | Sitcom |
| The Man in the High Castle | Prime Video | 2015–2019 | 4 | 40 | Thriller |
| Man, Moment, Machine | History | 2005–2006 | 2 | 24 | Documentary |
| Man of the People | NBC | 1991–1992 | 1 | 10 | Sitcom |
| Man on Fire | Netflix | 2026–on air | — | — | Crime |
| A Man on the Inside | Netflix | 2024–on air | 2 | 16 | Comedy |
| Man Seeking Woman | FX | 2015–2017 | 3 | 30 | Sitcom |
| The Man Show | Comedy Central | 1999–2004 | 6 | 112 | — |
| Man Up! | ABC | 2011 | 1 | 13 | Sitcom |
| Man v. Food | Travel Channel | 2008 | 10 | 175 | Documentary |
| Man vs. Cartoon | TruTV | 2009 | — | 6 | Reality |
| Man vs. Wild | Discovery Channel | 2006–2012 | 7 | 72 | Nature |
| The Man Who Fell to Earth | Showtime | 2022 | 1 | 10 | Science fiction |
| The Man Who Never Was | | 1966–1967 | 1 | 18 | — |
| Man with a Camera | ABC | 1958–1960 | 2 | 29 | Drama |
| Man with a Plan | CBS | 2016–2020 | 4 | 69 | Sitcom |
| Man Without a Gun | NTA Film Network | 1957–1959 | 2 | 52 | — |
| Man, Woman, Wild | Discovery Channel | 2010–2012 | 2 | 22 | Reality |
| Mancuso, F.B.I. | NBC | 1989–1990 | 1 | 20 | Detective |
| The Mandalorian | Disney+ | 2019–on air | 3 | 24 | Adventure |
| ManeaterMiniseries | Lifetime | 2009 | 1 | 2 | — |
| Manhattan | WGN America | 2014–2015 | 2 | 23 | Drama |
| The Manhattan Alien Abduction | Netflix | 2024–on air | — | 3 | Documentary |
| Manhattan, AZ | USA Network | 2000 | 1 | 13 | Comedy |
| Manhattan Love Story | ABC | 2014 | 1 | 11 | Sitcom |
| Manhunt | Syndication | 1959–1961 | 2 | 78 | Detective |
| Manhunt | UPN | 2001 | 1 | 6 | Reality |
| Manhunt | Discovery Channel | 2017–2020 | 2 | 18 | Drama |
| Manhunt | Apple TV | 2024 | — | 2 | Conspiracy fiction |
| The Manhunter | CBS | 1974–1975 | 1 | 23 | — |
| Maniac | Netflix | 2018 | 1 | 10 | Black comedy |
| Manifest | NBC, Netflix | 2018–2023 | 4 | 62 | Drama |
| Manimal | NBC | 1983 | 1 | 8 | Science fiction |
| Mankind: The Story of All of Us | History | 2012 | 1 | 12 | Non-fiction |
| Mann & Machine | NBC | 1992 | 1 | 9 | Science fiction |
| Mann & Wife | Bounce TV | 2015–2017 | 1 | 10 | Sitcom |
| Mannix | CBS | 1967–1975 | 8 | 194 | Crime |
| Manswers | Spike TV, Paramount Network | 2007–2011 | 4 | 39 | Documentary |
| Many Happy Returns | CBS | 1964–1965 | 1 | 26 | Sitcom |
| The Many Loves of Dobie Gillis | CBS | 1959–1963 | 4 | 147 | Teen sitcom |
| Mao Mao: Heroes of Pure HeartAnimated series | Cartoon Network | 2019–2020 | 1 | 40 | Fantasy |
| Mapleworth MurdersWeb series | Quibi | 2020 | — | — | — |
| Maradona in MexicoMiniseries | Netflix | 2019 | 1 | 7 | Documentary |
| Marble HornetsWeb series | YouTube | 2009–2014 | 3 | 130 | Found footage |
| Marblehead Manor | Syndication | 1987–1988 | 1 | 24 | Sitcom |
| Marcel's Quantum Kitchen | Syfy | 2011 | 1 | 6 | — |
| Marching Orders | Netflix | 2018–on air | — | — | Documentary |
| Marco PoloMiniseries | NBC | 1982 | 1 | 10 | Biographical |
| Marco Polo | Netflix | 2014–2016 | 2 | 21 | Drama |
| Marcus Welby, M.D. | ABC | 1969–1976 | 7 | 170 | Drama |
| Mare of EasttownMiniseries | HBO | 2021 | 1 | 7 | Crime |
| Marge and Jeff | DuMont | 1953–1954 | — | — | Sitcom |
| Margie | ABC | 1961–1962 | 1 | 26 | Sitcom |
| Margo's Got Money Troubles | Apple TV | 2026–on air | — | — | Drama |
| Mariah Carey's Magical Christmas Special | Apple TV | 2020–on air | — | — | Christmas music |
| Mariah's World | E! | 2016–2017 | 1 | 8 | Documentary |
| Marido En Alquiler | Telemundo | 2013–2014 | — | 141 | Telenovela |
| Marie | Hallmark Channel | 2012–2013 | 1 | 150 | Talk show |
| Marielena | Telemundo, TV Azteca | 1992–1993 | 1 | 228 | Telenovela |
| Mario Lopez: Saved by the Baby | VH1 | 2010–2011 | 1 | 10 | Reality |
| Mark & Olly: Living with the Tribes | Travel Channel | 2007 | 3 | — | Documentary |
| Marked | History | 2009 | — | 6 | Documentary |
| Marker | UPN | 1995 | 1 | 13 | Drama |
| Market Warriors | PBS | 2012–2013 | 1 | 20 | Reality |
| Market WatchNews program | CNBC | 1998–2002 | — | — | News |
| Markham | CBS | 1959–1960 | 1 | 59 | Crime |
| Marlo and the Magic Movie Machine | CBS | 1977–1980 | — | — | Children's |
| Marlon | NBC | 2017–2018 | 2 | 20 | Comedy |
| Maron | IFC | 2013–2016 | 4 | 49 | Comedy |
| Marriage Boot Camp | We TV | 2013 | 6 | 64 | Reality |
| The Marriage Ref | NBC | 2010–2011 | 2 | 20 | Reality |
| Married | FX | 2014–2015 | 2 | 23 | Sitcom |
| Married at First Sight | Lifetime, FYI | 2014 | 3 | 42 | Reality |
| Married in America | A&E | 2002 | — | 2 | Documentary |
| Married People | ABC | 1990–1991 | 1 | 18 | Sitcom |
| Married to Jonas | E! | 2012–2013 | 2 | 16 | Reality |
| Married to Medicine | Bravo | 2013 | 4 | 49 | Reality |
| Married to Medicine: Houston | Bravo | 2016 | 1 | 8 | Reality |
| Married to Medicine: Los Angeles | Bravo | 2019–2020 | 2 | 18 | Reality |
| Married to Rock | E! | 2010 | 1 | 8 | Reality |
| Married to the Kellys | ABC | 2003–2004 | 1 | 22 | Sitcom |
| Married... with Children | Fox | 1987–1997 | 11 | 259 | Sitcom |
| Marry MeMiniseries | Lifetime | 2010 | 1 | 2 | — |
| Marry Me | NBC | 2014–2015 | 1 | 18 | Sitcom |
| Marrying the Game | VH1 | 2012–2014 | 3 | 22 | Reality |
| Mars | National Geographic | 2016–2018 | 2 | 12 | Science fiction |
| The Marsha Warfield Show | NBC | 1990–1991 | 1 | — | Talk show |
| The Marshal | ABC | 1995 | 2 | 25 | Crime |
| The Marshal of Gunsight Pass | ABC | 1950 | 1 | 22 | Western |
| MarsupilamiAnimated series | CBS | 1993–1994 | 1 | 29 | Comedy |
| Martha | Syndication | 2005–2012 | 7 | 1,162 | Variety show |
| Martha & Snoop's Potluck Party Challenge | VH1 | 2016 | 1 | 5 | — |
| Martha SpeaksAnimated series | PBS Kids, TVO Media Education Group | 2008–2014 | 6 | 96 | Comedy |
| Martial Law | CBS | 1998–2000 | 2 | 44 | Crime |
| The Martian ChroniclesMiniseries | NBC | 1980 | — | 3 | Science fiction |
| Martin | Fox | 1992–1997 | 5 | 132 | Sitcom |
| Martin Kane, Private Eye | NBC | 1949–1954 | — | — | Crime fiction |
| The Martin Short Show | NBC | 1994 | 1 | 8 | Sitcom |
| Marvel's Iron Fist | Netflix | 2017–2018 | 2 | 23 | Fantasy |
| Marvel's Moon Girl and Devil DinosaurAnimated series | Disney Channel | 2023–2025 | 2 | 30 | Animated film with lgbt character(s) |
| Marvel's Spider-ManAnimated series | Disney XD | 2017–2020 | 3 | 58 | Action |
| Marvel Studios: Legends | Disney+ | 2021–on air | 2 | 46 | Superhero |
| The Marvel Super HeroesAnimated series | Syndication | 1966 | 1 | 65 | — |
| Marvel ZombiesAnimated series | Disney+ | 2025 | — | 4 | Zombie apocalyptic |
| The Marvelous Misadventures of FlapjackAnimated series | Cartoon Network | 2008–2010 | 3 | 46 | Children's |
| The Marvelous Mrs. Maisel | Prime Video | 2017–2023 | 5 | 43 | Drama |
| Marvel’s The Defenders | Netflix | 2017 | 1 | 8 | Fantasy |
| Marvin Marvin | Nickelodeon, TeenNick | 2012–2013 | 1 | 19 | Teen sitcom |
| Mary | CBS | 1978 | 1 | 3 | Variety show |
| Mary | CBS | 1985–1986 | 1 | 13 | Sitcom |
| Mary Hartman, Mary Hartman | Syndication | 1976–1977 | 2 | 325 | Sitcom |
| Mary + Jane | MTV | 2016 | 1 | 10 | Comedy |
| Mary-Kate and Ashley in Action!Animated series | ABC | 2001–2002 | 1 | 26 | — |
| Mary Kay and Johnny | DuMont, NBC | 1947–1950 | — | — | Sitcom |
| Mary Shelley's FrankenholeAnimated series | Adult Swim, Cartoon Network | 2010–2012 | 2 | 20 | Comedy |
| The Mary Tyler Moore Hour | CBS | 1979 | 1 | 11 | Sitcom |
| The Mary Tyler Moore Show | CBS | 1970–1977 | 7 | 168 | Sitcom |
| Mary Tyler Moore: The 20th Anniversary Show | CBS | 1991 | — | — | — |
| Maryoku YummyAnimated series | Discovery Family | 2010 | 1 | 26 | Adventure |
| Más Sabe el Diablo | Telemundo | 2009–2010 | 1 | 182 | Telenovela |
| MasadaMiniseries | ABC | 1981 | 1 | 4 | Drama |
| The Mask: Animated SeriesAnimated series | CBS | 1995–1997 | 3 | 54 | Fantasy |
| The Mask of Analia | NBC, Telemundo | 2008–2009 | 1 | 178 | Romance |
| The Masked Dancer | Fox | 2020–2021 | — | — | Reality |
| Masked Rider | Fox Kids | 1995–1996 | 1 | 40 | Action |
| The Masked Singer | Fox | 2019–on air | 9 | 96 | Game show |
| Masquerade | ABC | 1983–1984 | 1 | 13 | — |
| Masquerade Party | NBC | 1952–1960 | 8 | 39 | Panel game |
| The Master | NBC | 1984 | 1 | 13 | Action |
| Master of Champions | ABC | 2006 | — | 6 | Reality |
| Master of None | Netflix | 2015–2021 | 3 | 25 | Comedy |
| Master of the GameMiniseries | CBS | 1984 | — | 3 | — |
| Master of the Mix | BET | 2010–2013 | 3 | 28 | Reality |
| MasterChef | Fox | 2010 | 12 | 205 | Reality |
| MasterChef Junior | Fox | 2013 | 3 | 22 | Reality |
| MasterChef Latino | Telemundo | 2018–2019 | 2 | 26 | Reality |
| MasterChef Latinos | Estrella TV | 2022 | 1 | 15 | Reality |
| MasterChef USA | PBS | 2000–2001 | — | 26 | Reality |
| Masters of Horror | Showtime | 2005–2007 | 2 | 26 | Anthology |
| Masters of Illusion | The CW, Ion Television | 2000 | 4 | 42 | — |
| Masters of Science Fiction | ABC | 2007 | 1 | 6 | Science fiction |
| Masters of Sex | Showtime | 2013–2016 | 4 | 46 | Drama |
| Masters of the AirMiniseries | Apple TV | 2024 | — | 9 | War |
| Masters of the Maze | Freeform | 1994–1995 | 2 | 80 | Game show |
| Masters of the Universe: RevelationAnimated series | Netflix | 2021 | 2 | 15 | Science fiction |
| Matador | El Rey Network | 2014 | 1 | 13 | Action |
| Match Game | CBS, ABC | 1962–2021 | — | 1,760 | Panel game |
| The Match Game-Hollywood Squares Hour | NBC | 1983–1984 | — | 191 | Game show |
| Mathnet | PBS | 1987–1992 | 5 | 30 | Police procedural |
| Matinee Theater | NBC | 1955–1958 | 3 | 650 | Anthology |
| Matlock | NBC | 1986–1995 | 9 | 194 | Legal drama |
| Matlock | CBS | 2024–on air | 2 | 35 | — |
| MatPat's Game Lab | YouTube Premium | 2016 | 1 | 8 | Reality |
| Matt Helm | ABC | 1975–1976 | 1 | 14 | Mystery |
| Matt Houston | ABC | 1982–1985 | 3 | 67 | Drama |
| Matt Waters | CBS | 1996 | 1 | 6 | Drama |
| Maude | CBS | 1972–1978 | 6 | 141 | Sitcom |
| Maui Fever | MTV | 2007 | 1 | 8 | Reality |
| Maury | | 1991–2022 | 31 | 2,640 | Tabloid talk show |
| Maverick | ABC | 1957–1962 | 5 | 124 | Comedy |
| Max & Shred | TeenNick, Nickelodeon | 2014–2016 | 2 | 34 | Teen sitcom |
| Max & the MidknightsAnimated series | Nickelodeon | 2024–2026 | 2 | 10 | — |
| Max Headroom | ABC | 1987–1988 | 2 | 14 | Cyberpunk |
| Max Monroe: Loose Cannon | CBS | 1990 | 1 | 5 | — |
| Max SteelAnimated series | Cartoon Network, The WB | 2000–2002 | 3 | 36 | Science fiction |
| Max SteelAnimated series | Disney XD | 2013–2015 | 2 | 54 | Superhero |
| Maxie's WorldAnimated series | Syndication | 1987–1989 | 1 | 32 | Children's |
| Maximum Bob | ABC | 1998 | 1 | 7 | Drama |
| Maximum Pleasure Guaranteed | Apple TV | 2026–on air | — | — | Black comedy |
| The Maxx | MTV | 1995 | — | 13 | Comedy-drama |
| Maya | NBC | 1967–1968 | 1 | 18 | — |
| Maya & Marty | NBC | 2016 | 1 | 3 | Variety show |
| Maya & MiguelAnimated series | PBS, PBS Kids Go! | 2004–2007 | 5 | 65 | Animated sitcom |
| Maya and the ThreeMiniseries | Netflix | 2021 | 1 | 9 | Fantasy |
| Mayans M.C. | FX | 2018–2023 | 5 | 50 | Drama |
| Maybe It's Me | The WB | 2001–2002 | 1 | 22 | Teen sitcom |
| Maybe This Time | ABC | 1995–1996 | 1 | 18 | Sitcom |
| Mayberry R.F.D. | CBS | 1968–1971 | 3 | 78 | Sitcom |
| Mayfair Witches | AMC | 2023–on air | 2 | 16 | Horror |
| The Mayor | ABC | 2017–2018 | 1 | 11 | Comedy |
| Mayor of Kingstown | Paramount+ | 2021–on air | 4 | 40 | — |
| McBride | Hallmark Channel | 2005–2008 | — | 10 | Drama |
| The McCarthys | CBS | 2014–2015 | 1 | 15 | Comedy |
| McCartney 3,2,1 | Hulu | 2021 | — | — | Documentary |
| McClain's Law | NBC | 1981–1982 | 1 | 16 | Police drama |
| McCloud | NBC | 1970–1977 | 7 | 46 | Crime |
| McCoy | NBC | 1975–1976 | 1 | 5 | Drama |
| McDuff, the Talking Dog | NBC | 1976 | — | 13 | — |
| McHale's Navy | ABC | 1962–1966 | 4 | 138 | Sitcom |
| McKeever and the Colonel | NBC | 1962–1963 | — | 26 | Sitcom |
| McKenna | ABC | 1994–1995 | 1 | 13 | — |
| The McLaughlin GroupNews program | Syndication | 1982–2020 | — | — | Talk show |
| The McLean Stevenson Show | NBC | 1976–1977 | 1 | 12 | Comedy |
| McMafia | AMC, BBC One | 2018 | 1 | 8 | Crime |
| McMillan & Wife | NBC | 1971–1977 | 6 | 40 | Drama |
| McMillionsMiniseries | HBO | 2020 | 1 | 6 | Documentary |
| MDs | ABC | 2002 | 1 | 11 | Medical drama |
| Me and Maxx | NBC | 1980 | 1 | 10 | Sitcom |
| Me and My Grandma | YouTube Premium | 2017 | 1 | 6 | Comedy |
| Me and the Boys | ABC | 1994–1995 | 1 | 19 | Black sitcom |
| Me and the Chimp | CBS | 1972 | 1 | 13 | Sitcom |
| Me, Myself & I | CBS | 2017–2018 | 1 | 13 | — |
| Meatballs & SpaghettiAnimated series | CBS | 1982–1983 | 1 | 21 | Children's |
| MeatEater | Sportsman Channel, Netflix | 2012 | 10 | 118 | Reality |
| Mech CadetsAnimated series | Netflix | 2023–on air | 1 | 10 | Adventure |
| Mech-X4 | Disney Channel, Disney XD | 2016–2018 | 1 | 4 | Action |
| The Mechanical Universe | PBS | 1985–1986 | 1 | 52 | Documentary |
| Mecum Dealmakers | NBCSN | 2014–2015 | 2 | 18 | — |
| Medal of Honor | Netflix | 2018–on air | 1 | 8 | Docudrama |
| Media Buzz | Fox News | 2013 | — | — | Media journalism |
| Medic | NBC | 1954–1956 | 2 | 59 | Medical drama |
| Medical Center | CBS | 1969–1976 | 7 | 171 | Medical drama |
| Medical Horizons | ABC | 1955–1956 | 1 | 26 | Documentary |
| Medical Investigation | NBC | 2004–2005 | 1 | 20 | Drama |
| Medical Police | Netflix | 2020–on air | 1 | 10 | Thriller |
| Medical Story | NBC | 1975–1976 | 1 | 12 | Anthology |
| Medicine Ball | Fox | 1995 | 1 | 9 | Medical drama |
| Medium | CBS, NBC | 2005–2011 | 7 | 130 | Thriller |
| Meego | CBS | 1997 | 1 | 13 | Science fiction |
| Meet Corliss Archer | Syndication | 1954 | 1 | 39 | Sitcom |
| Meet McGraw | NBC | 1957–1958 | — | 42 | Drama |
| Meet My Folks | NBC, MyNetworkTV | 2002–2003 | — | 20 | Reality |
| Meet the Barkers | MTV | 2005–2006 | 2 | 16 | Reality |
| Meet the Natives: USA | Travel Channel | 2009 | 1 | 6 | Reality |
| Meet the PressNews program | NBC | 1947 | 70 | 1,414 | Public affairs |
| Meet the Press NOW | MS NOW | 2015–2022 | — | — | Opinion journalism |
| Meet the Smiths | TBS | 2015 | 1 | 6 | Comedy |
| Meet The TeamMiniseries | YouTube | 2007–2012 | — | 10 | Machinima |
| Meeting of Minds | PBS | 1977–1981 | 4 | 24 | Documentary |
| Mega Disasters | History | 2006–2008 | 3 | 38 | Documentary |
| Mega ManAnimated series | Syndication | 1994–1995 | 2 | 27 | Comedy |
| Mega Man: Fully ChargedAnimated series | Cartoon Network, WildBrainTV | 2018–2019 | — | 26 | — |
| Mega Movie Magic | Discovery Channel | 1998–2004 | 7 | — | — |
| Mega64Web series | public-access television | 2004 | 3 | 17 | Sketch comedy |
| The Megan Mullally Show | Syndication | 2006–2007 | — | 71 | Talk show |
| Megan Wants a Millionaire | VH1 | 2009 | 1 | 3 | Reality |
| Megas XLRAnimated series | Cartoon Network | 2002–2005 | 2 | 26 | Children's |
| MegaStructures | National Geographic | 2004 | 6 | 100 | Documentary |
| Megyn Kelly TodayNews program | NBC | 2000–2017 | 1 | 282 | Talk show |
| Mel B: It's a Scary World | Esquire Network | 2010 | 1 | 10 | Reality |
| The Mel Robbins Show | Syndication | 2019–2020 | 1 | — | — |
| Melba | CBS | 1986 | 1 | 6 | Sitcom |
| Melissa & Joey | Freeform | 2010–2015 | 4 | 104 | Comedy |
| Melody Street | DuMont | 1953–1954 | 1 | 20 | — |
| Melrose Place | Fox | 1992–1999 | 7 | 226 | Soap opera |
| Melrose Place | The CW | 2009–2010 | 1 | 18 | Drama |
| The Meltdown with Jonah and Kumail | Comedy Central | 2014–2016 | 2 | 16 | — |
| Memory of a Killer | Fox | 2026–on air | 1 | 10 | Drama |
| Memphis Beat | TNT | 2010–2011 | 2 | 20 | Comedy-drama |
| Men | ABC | 1989 | 1 | 6 | Drama |
| Men at Work | Turner Broadcasting System, TBS | 2012–2014 | 3 | 30 | Sitcom |
| Men Behaving Badly | NBC | 1996–1997 | 2 | 35 | Sitcom |
| Men in Black: The SeriesAnimated series | CBS, The WB | 1997–2002 | 4 | 53 | Children's |
| Men in Trees | ABC | 2006–2008 | 2 | 36 | Comedy-drama |
| Men into Space | CBS | 1959–1960 | 1 | 38 | Science fiction |
| Men of a Certain Age | TNT | 2009–2011 | 2 | 22 | Comedy-drama |
| Men of Annapolis | Syndication | 1957–1958 | 1 | 41 | Drama |
| The Men Who Built AmericaMiniseries | History | 2012 | 1 | 4 | Docudrama |
| Men, Women & Dogs | The WB | 2001 | 1 | 13 | Comedy |
| Mental | Fox | 2009 | 1 | 13 | Drama |
| Mental Samurai | Fox | 2019–2021 | — | — | Game show |
| The Mentalist | CBS | 2008–2015 | 7 | 151 | Drama |
| Mercy | NBC | 2009–2010 | 1 | 22 | Drama |
| Mercy Point | UPN | 1998–1999 | 1 | 8 | Science fiction |
| Mercy Street | PBS | 2016–2017 | 1 | 6 | Drama |
| The Meredith Vieira Show | Syndication | 2014–2016 | 2 | 290 | — |
| MerlinMiniseries | NBC | 1998 | 1 | 2 | Fantasy |
| Mermaid Magic | Netflix | 2024–on air | 1 | 10 | — |
| Merrie Melodies Starring Bugs Bunny & FriendsAnimated series | Syndication | 1990–1994 | 1 | 65 | Comedy |
| Merry Happy Whatever | Netflix | 2019–on air | 1 | 8 | Sitcom |
| Merv Griffin's Crosswords | Syndication | 2007–2008 | 1 | 225 | — |
| The Merv Griffin Show | NBC | 1962–1986 | — | 4,855 | — |
| The Messengers | The CW | 2015 | 1 | 13 | Science fiction |
| Messiah | Netflix | 2020 | 1 | 10 | Thriller |
| MetalocalypseAnimated series | Adult Swim, Cartoon Network | 2006–2013 | 4 | 63 | Music |
| Metástasis | Caracol Televisión | 2014 | 5 | 62 | Police |
| MeteorMiniseries | NBC | 2009 | — | 2 | Science fiction |
| Meteorite Men | Science Channel | 2009–2012 | 3 | 23 | Reality |
| Method & Red | Fox | 2004 | 1 | 13 | Sitcom |
| Metropolis, Illinois Movie Car | | 2027upcoming | 1 | 10 | Drama |
| Mexico's Next Top Model | AXN White | 2009–2014 | 5 | 62 | Reality |
| MGM Parade | ABC | 1955–1956 | 1 | 34 | Documentary |
| Mi Corazón Insiste… en Lola Volcán | Telemundo | 2011 | 1 | 133 | Telenovela |
| Miami Animal Police | Animal Planet | 2004 | — | — | Docu-soap |
| Miami Ink | TLC | 2005–2008 | 5 | 87 | Reality |
| Miami Medical | CBS | 2010 | 1 | 13 | Medical drama |
| Miami Monkey | VH1 | 2013 | 1 | 11 | Reality |
| Miami Social | Bravo | 2009 | 1 | 7 | Reality |
| Miami Vice | NBC | 1984–1990 | 5 | 112 | Crime |
| Michael & Michael Have Issues | Comedy Central | 2009 | 1 | 7 | — |
| Michael Hayes | CBS | 1997–1998 | 1 | 22 | Drama |
| The Michael J. Fox Show | NBC | 2013–2014 | 1 | 22 | Sitcom |
| The Michael Richards Show | NBC | 2000 | 1 | 9 | Sitcom |
| The Michael Vick Project | BET | 2010 | 1 | 8 | Reality |
| The Mick | Fox | 2017–2018 | 2 | 37 | Sitcom |
| Mickey | ABC | 1964 | 1 | 17 | Sitcom |
| Mickey MouseAnimated series | Disney Channel | 2013–2019 | 5 | 96 | Comedy |
| The Mickey Mouse Club | ABC, Syndication | 1955–1959 | 14 | 360 | Music |
| Mickey Mouse ClubhouseAnimated series | Disney Jr., Disney Channel | 2006–2016 | 4 | 125 | Comedy |
| Mickey Mouse Clubhouse+Animated series | Disney Jr. | 2025–on air | 1 | 20 | Comedy |
| Mickey Mouse FunhouseAnimated series | Disney Jr. | 2021–2025 | 3 | 85 | Children's |
| Mickey Mouse Mixed-Up AdventuresAnimated series | Disney Jr. | 2017–2021 | 3 | 87 | Children's |
| Mickey Mouse WorksAnimated series | ABC | 1999–2000 | 2 | 25 | Comedy |
| The Mickey Rooney Show: Hey, Mulligan | NBC | 1954–1955 | 1 | 33 | Sitcom |
| Mickey Spillane's Mike Hammer | Syndication | 1958–1959 | 2 | 78 | Crime |
| Mickey Spillane's Mike Hammer | CBS | 1984–1987 | 3 | 46 | Crime |
| Mickie Finn's | NBC | 1966 | 1 | 16 | Variety show |
| Micro Ventures | NBC | 1968 | — | 4 | — |
| Mid-Century Modern | Hulu | 2025 | 1 | 10 | Sitcom |
| The Middle | ABC | 2009–2018 | 9 | 215 | Sitcom |
| Middle Ages | CBS | 1992 | 1 | 6 | Comedy-drama |
| Middle of the Night Show | MTV | 2015 | 1 | 9 | — |
| Middle School MogulsAnimated series | Nickelodeon | 2019 | — | — | Children's |
| The Middleman | Freeform | 2008 | 1 | 12 | Science fiction |
| Middlemost PostAnimated series | Nickelodeon | 2021–2022 | 2 | 33 | Children's |
| @midnight | Comedy Central | 2013–2017 | 3 | 600 | Improvisational theatre |
| Midnight Blue | Channel J | 1974–2003 | — | — | — |
| Midnight Caller | NBC | 1988–1991 | 3 | 61 | Drama |
| The Midnight Club | Netflix | 2022 | 1 | 10 | Thriller |
| The Midnight GospelAnimated series | Netflix | 2020–on air | 1 | 8 | Adult animation |
| Midnight Mass | Netflix | 2021 | 1 | 7 | Horror |
| The Midnight Special | NBC | 1973–1981 | — | 450 | Variety show |
| Midnight, Texas | NBC | 2017–2018 | 2 | 19 | Drama |
| The Mighty B!Animated series | Nickelodeon | 2008–2011 | 2 | 40 | Comedy |
| Mighty DucksAnimated series | ABC | 1996–1997 | 1 | 26 | Comedy |
| The Mighty Ducks: Game Changers | Disney Channel, Disney+ | 2021–2022 | 2 | 20 | Comedy-drama |
| Mighty Express | Netflix | 2020–2022 | 6 | 38 | Children's |
| The Mighty HeroesAnimated series | CBS | 1966–1967 | 1 | 20 | Children's |
| The Mighty Jungle | Freeform | 1994 | 1 | 26 | Sitcom |
| Mighty MagiswordsAnimated web series | Cartoon Network | 2016–2019 | 2 | 92 | — |
| Mighty MaxAnimated series | Syndication | 1993–1994 | 2 | 40 | — |
| Mighty Med | Disney XD | 2013–2015 | 2 | 44 | Medical drama |
| Mighty MonsterWheelies | Netflix | 2024–on air | — | — | Children's |
| Mighty Morphin Alien Rangers | Fox | 1996 | 1 | 10 | Adventure |
| Mighty Morphin Power Rangers | Fox | 1993–1995 | 3 | 145 | Teen |
| Mighty Mouse: The New AdventuresAnimated series | CBS | 1987–1988 | 2 | 19 | — |
| The Mighty NeinAnimated series | Prime Video | 2025–on air | — | — | Adult animation |
| MikeMiniseries | Hulu | 2022 | 1 | 8 | — |
| Mike & Mike | ESPN Radio | 2000–2017 | — | — | — |
| Mike & Molly | CBS | 2010–2016 | 6 | 127 | Sitcom |
| The Mike Douglas Show | Syndication | 1961–1981 | 21 | 4,017 | — |
| Mike Hammer, Private Eye | Syndication | 1997–1998 | — | 26 | — |
| Mike Judge Presents: Tales from the Tour BusAnimated series | Cinemax | 2017 | 2 | 16 | — |
| Mike, Lu & OgAnimated series | Cartoon Network | 1999–2001 | 2 | 26 | Comedy |
| The Mike O'Malley Show | NBC | 1999 | 1 | 8 | Sitcom |
| Mike's Super Short Show | Disney Channel | 2002–2007 | 5 | 27 | — |
| Mike Tyson MysteriesAnimated series | Cartoon Network, Adult Swim | 2014–2020 | 2 | 30 | Comedy |
| Milagros de Navidad | Telemundo | 2017 | 1 | 20 | — |
| Mildred PierceMiniseries | HBO | 2011 | 1 | 5 | Drama |
| Millennium | Fox | 1996–1999 | 3 | 67 | Drama |
| Millennium: Tribal Wisdom and the Modern World | Global Television Network | 1992 | — | 10 | Documentary |
| The Millers | CBS | 2013–2015 | 2 | 34 | LGBTQ |
| Million Dollar Beach House | Netflix | 2020–on air | 1 | 6 | Reality |
| Million Dollar Challenge | Fox | 2009–2010 | 2 | 13 | — |
| Million Dollar Extreme Presents: World Peace | Adult Swim | 2016 | 1 | 6 | Post-apocalyptic |
| Million Dollar Listing Los Angeles | Bravo | 2006–2020 | 8 | 78 | Reality |
| Million Dollar Listing Miami | Bravo | 2014 | 1 | 8 | Reality |
| Million Dollar Listing New York | Bravo | 2012–2021 | 7 | 87 | Reality |
| Million Dollar Matchmaker | We TV | 2016 | 1 | 3 | Reality |
| Million Dollar Mile | CBS | 2019 | — | — | Reality |
| Million Dollar Money Drop | Fox | 2010–2011 | 1 | 12 | Game show |
| Million Dollar Password | CBS | 2008 | 2 | — | Game show |
| Million Dollar Secret | Netflix | 2025 | 1 | 8 | Reality competition |
| A Million Little Things | ABC | 2018–2023 | 5 | 87 | Family drama |
| The Million Second Quiz | NBC | 2013 | 1 | 10 | Game show |
| The Millionaire | CBS | 1955–1960 | 6 | 206 | Anthology |
| Millionaire Matchmaker | Bravo | 2008–2015 | 8 | 106 | Reality |
| Milo Murphy's LawAnimated series | Disney XD | 2016–2019 | 2 | 35 | Comedy |
| Milton the Monster | ABC | 1965–1968 | 1 | 26 | — |
| Mina and the CountAnimated series | Cartoon Network, Nickelodeon | 1995–1999 | 1 | 6 | — |
| The Mind, Explained | Netflix | 2019–2021 | 1 | 5 | Docu-soap |
| Mind FieldWeb series | YouTube Premium | 2017 | — | 24 | Education |
| Mind Games | ABC | 2014 | 1 | 13 | Drama |
| The Mind of a Chef | PBS | 2012–2017 | 5 | 86 | — |
| Mind of a Man | Game Show Network | 2014 | 1 | 40 | Game show |
| Mind of Mencia | Comedy Central | 2005–2008 | 4 | 52 | Comedy |
| The Mind of the Married Man | HBO | 2001–2002 | 2 | 21 | Comedy-drama |
| Mind Over Murder | HBO | 2022 | 1 | 6 | Documentary |
| Mindhunter | Netflix | 2017–2019 | 2 | 19 | Drama |
| Mindreaders | NBC | 1979–1980 | — | 109 | — |
| The Mindy Project | Fox, Hulu | 2012–2017 | 6 | 117 | Sitcom |
| MinecraftAnimated series | Netflix | 2024–on air | — | — | — |
| The Miniature Wife | Peacock | 2026–on air | — | 10 | Romantic comedy |
| Minnie's Bow-ToonsAnimated series | Disney Jr., Disney Channel | 2011–2016 | 5 | 40 | Children's |
| The Minor Accomplishments of Jackie Woodman | IFC | 2006–2007 | 2 | 16 | Comedy |
| Minor Adjustments | NBC | 1995–1996 | 1 | 20 | Sitcom |
| MinoriteamAnimated series | Adult Swim | 2006 | 1 | 19 | Adult animation |
| Minority Report | Fox | 2015 | 1 | 10 | Science fiction |
| MinusculeAnimated series | Disney Channel, France 2 | 2006–2012 | 2 | 78 | Live action & animation |
| Minute to Win It | NBC, Game Show Network | 2010–2011 | — | — | Game show |
| A Minute with Stan Hooper | Fox | 2003 | 1 | 13 | Sitcom |
| Minx | Starz, Cinemax | 2022–2023 | 2 | 18 | Comedy |
| Mira quien baila | Univision | 2010 | 9 | 81 | — |
| Mira, Royal DetectiveAnimated series | Disney Jr. | 2020–2022 | 2 | 54 | Mystery |
| Miracle's BoysMiniseries | TeenNick | 2005 | 1 | 6 | — |
| Miracle Workers | TBS | 2019–2023 | 4 | 37 | Anthology |
| Miracles | ABC | 2003 | 1 | 13 | Drama |
| The Mis-Adventures of Awkward Black GirlWeb series | YouTube | 2011–2013 | 2 | 25 | Comedy |
| The Misadventures of Sheriff Lobo | NBC | 1979–1981 | 2 | 38 | Sitcom |
| Misery Index (TV series) | TBS | 2019–on air | 3 | 38 | Game show |
| Misery Loves Company | Fox | 1995 | 1 | 8 | Sitcom |
| Misfit Garage | Discovery Channel | 2014–2018 | 3 | 20 | — |
| Misfits of Science | NBC | 1985–1986 | 1 | 16 | Comedy-drama |
| The Misfortune of Being NedWeb series | YouTube | 2013–2014 | 2 | 20 | Animated short |
| Miss Advised | Bravo | 2012 | 1 | 8 | Reality |
| Miss Guided | ABC | 2008 | 1 | 7 | Sitcom |
| Miss Match | NBC | 2003 | 1 | 18 | Comedy-drama |
| Miss Scarlet | PBS, Alibi | 2020–on air | 6 | 36 | Mystery |
| Miss Seventeen | MTV | 2005 | 1 | 10 | Reality |
| Miss Susan | NBC | 1951 | 1 | 218 | Soap opera |
| Miss U Much | VH1 | 2012–2013 | 1 | 8 | Reality |
| Missing | Lifetime, W Network | 2003–2006 | 3 | 55 | Crime |
| Missing | ABC | 2012 | 1 | 10 | Drama |
| The Missing | BBC One | 2014–2016 | 2 | 16 | Drama |
| Missing Link | ESPN Classic | 2007 | 1 | 13 | — |
| Missing Links | ABC, NBC | 1963–1964 | 2 | 135 | Panel game |
| Missing Persons | ABC | 1993–1994 | 1 | 17 | — |
| Mission Force OneAnimated series | Disney Channel, Disney Jr. | 2015–2018 | 1 | 12 | Action |
| Mission Genesis | Syfy, YTV | 1997 | 1 | 13 | Thriller |
| Mission HillAnimated series | The WB | 1999–2002 | 1 | 13 | Adult animation |
| Mission: Impossible | CBS | 1966–1973 | 7 | 171 | Crime |
| Mission: Impossible | ABC | 1988–1990 | 2 | 35 | Action |
| Mission: Magic!Animated series | ABC | 1973 | 1 | 16 | Comedy |
| Mission Man Band | VH1 | 2007–2008 | 1 | 7 | Reality |
| The Mississippi | CBS | 1983–1984 | 2 | 23 | — |
| Mississippi Rising | MS NOW | 2005 | — | — | — |
| The Mist | Spike TV | 2017 | 1 | 10 | Science fiction |
| Mister Ed | Syndication | 1961–1966 | 6 | 143 | Sitcom |
| Mister Magoo | NBC | 1960–1962 | 3 | 184 | — |
| Mister Roberts | NBC | 1965–1966 | 1 | 30 | Sitcom |
| Mister Rogers' Neighborhood | National Educational Television, PBS | 1968–2001 | 31 | 905 | — |
| Mister Sterling | NBC | 2003 | 1 | 10 | — |
| Mister TAnimated series | NBC | 1983–1985 | 2 | 30 | Action |
| Mistral's DaughterMiniseries | CBS | 1984 | — | 3 | — |
| Mistresses | ABC | 2013–2016 | 4 | 52 | Drama |
| The Mists of AvalonMiniseries | TNT | 2001 | — | 2 | Drama |
| Mixed-ish | ABC | 2019–2021 | 2 | 36 | Sitcom |
| Mixed Nuts | ABC | 1959 | — | — | Drama |
| MixelsAnimated series | Cartoon Network | 2014–2016 | 3 | 31 | Comedy |
| Mixology | ABC | 2014 | 1 | 13 | Sitcom |
| Miz & Mrs. | USA Network | 2018–2022 | 3 | 50 | Reality |
| MMA Live | ESPN | 2010–2011 | 2 | — | — |
| Mo | Netflix | 2022–on air | 2 | 16 | Comedy-drama |
| Mo'Nique's Fat Chance | Oxygen | 2005–2007 | 3 | — | Reality |
| The Mo'Nique Show | BET | 2009–2011 | 2 | 251 | — |
| Mob City | TNT | 2013 | 1 | 6 | Neo-noir |
| The Mob Doctor | Fox | 2012–2013 | 1 | 13 | Drama |
| Mob Wives | VH1 | 2011–2016 | 6 | 82 | Reality |
| Mob Wives Chicago | VH1 | 2012 | 1 | 11 | Reality |
| Mob Wives: The Sit Down | VH1 | 2012 | 1 | 7 | Reality |
| Mobbed | Fox | 2011–2013 | 1 | 11 | Reality |
| Mobile One | ABC | 1975–1976 | 1 | 11 | — |
| MobLand | Paramount+ | 2025–on air | 2 | 14 | Crime drama |
| Mobster Confessions | Discovery Channel | 2012 | 1 | 6 | Crime |
| Mobsters | FYI | 2007–2012 | 4 | 49 | Documentary |
| Moby Dick and Mighty MightorAnimated series | CBS | 1967–1968 | 2 | 18 | Fantasy |
| Mockingbird Lane | NBC | 2012 | 1 | 1 | Black comedy |
| The Mod Squad | ABC | 1968–1973 | 5 | 123 | — |
| A Model Life | TLC | 2007 | — | 8 | Reality |
| Models Inc. | Fox | 1994–1995 | 1 | 29 | Soap opera |
| Models of the Runway | Lifetime | 2009–2010 | 2 | 28 | Reality |
| Modern Family | ABC | 2009–2020 | 11 | 250 | Sitcom |
| Modern Love | Prime Video | 2019–2021 | 2 | 16 | Romantic comedy |
| Modern Marvels | H2, History | 1995–2015 | 19 | 690 | — |
| Modern Men | The WB | 2006 | 1 | 7 | Sitcom |
| Moesha | UPN | 1996–2001 | 6 | 127 | Sitcom |
| Moises Rules! | Disney XD | 2009 | 1 | 4 | Children's |
| The Mole | ABC | 2001–2008 | 5 | 45 | Reality |
| Molloy | Fox | 1990 | 1 | 7 | Teen sitcom |
| Molly of DenaliAnimated series | PBS, PBS Kids | 2019–on air | 4 | 67 | Children's |
| Moloney | CBS | 1996–1997 | 1 | 21 | — |
| Mom | CBS | 2013–2021 | 8 | 170 | Sitcom |
| The Moment | USA Network | 2013 | 1 | 9 | Reality |
| The Moment of Truth | Fox | 2008 | 2 | — | Quiz show |
| Momma's Boys | NBC | 2008–2009 | 1 | 11 | Reality |
| The Mommies | NBC | 1993–1995 | 2 | 37 | Sitcom |
| Mommy XXX | Crackle | 2009 | 1 | 13 | — |
| Mona McCluskey | NBC | 1965 | 1 | 26 | Sitcom |
| Monarch | Fox | 2022 | 1 | 11 | Drama |
| Monarch Cove | Lifetime | 2006 | 1 | 14 | Soap opera |
| Monarch: Legacy of Monsters | Apple TV | 2023–on air | 2 | 10 | Kaiju |
| Monday Mornings | TNT | 2013 | 1 | 10 | Drama |
| Monday Night Countdown | ABC, ESPN | 1993 | — | — | Sports |
| Monday Night Football | ABC, ESPN+ | 1970 | 54 | 718 | Sports |
| Monday Night Golf | ESPN on ABC | 1999 | — | 8 | — |
| Money, ExplainedMiniseries | Netflix | 2021 | 1 | 5 | Popular science |
| Money Hungry | | 2010 | 1 | 10 | Reality |
| Money Movers | CNBC | 2014–2021 | — | — | News |
| Money Talks | Playboy TV | 2007–2017 | 1 | 119 | Pornographic |
| Mongo Wrestling AllianceAnimated series | Cartoon Network, Adult Swim | 2011 | 1 | 10 | Adult animation |
| Monica: Still Standing | BET | 2009–2010 | 1 | 12 | Reality |
| Monica the Medium | Freeform | 2015–2016 | 2 | 11 | — |
| Monk | USA Network | 2002–2009 | 8 | 125 | Detective |
| The Monkees | NBC | 1966–1968 | 2 | 58 | Sitcom |
| Monopoly | ABC | 1990 | — | 12 | — |
| The Monroes | ABC | 1966–1967 | 1 | 26 | Soap opera |
| The Monroes | ABC | 1995 | — | — | Soap opera |
| Monsieur SpadeMiniseries | AMC+, AMC | 2024 | 1 | 6 | Neo-noir |
| Monster Bug Wars | Discovery Channel | 2011–2012 | 2 | 12 | Documentary |
| Monster Force | Universal Pictures | 1994 | — | 13 | — |
| Monster Garage | Discovery Channel | 2002–2006 | 5 | 80 | Reality |
| Monster HighAnimated web series | YouTube | 2010–2018 | 6 | 182 | Comedy |
| Monster HighAnimated series | Nickelodeon | 2022–2024 | 2 | 33 | Children's |
| Monster House | Discovery Channel | 2003–2006 | — | 60 | Reality |
| Monster Man | Syfy | 2012 | 1 | 6 | Reality |
| Monster ManiaAnimated series | Syndication, CITV | 1995–1996 | 1 | 26 | Comedy |
| Monster Squad | NBC | 1976–1977 | — | 13 | Vampire |
| MonsterQuest | History | 2007–2010 | 4 | 47 | Documentary |
| Monsters | Syndication | 1988–1991 | 3 | 72 | Anthology |
| Monsters at WorkAnimated series | Disney+ | 2021–on air | — | 20 | Comedy |
| Monsters Inside Me | Animal Planet | 2009–2017 | 6 | 56 | Documentary |
| Monsters Inside: The 24 Faces of Billy Milligan | Netflix | 2021 | 1 | 4 | Documentary |
| Monsters Resurrected | Discovery Channel | 2009 | 1 | 6 | Nature documentary |
| Monsters vs. AliensAnimated series | Nickelodeon | 2013–2014 | 1 | 26 | Comedy |
| Monte CarloMiniseries | CBS | 1986 | — | 2 | — |
| The Montefuscos | NBC | 1975 | 1 | 8 | Comedy |
| The Montel Williams Show | Syndication | 1991–2008 | 17 | 4,325 | Talk show |
| Monty | Fox | 1994 | 1 | 13 | Sitcom |
| Monty Nash | Syndication | 1971 | 1 | 14 | Detective |
| Monty Python's Personal BestMiniseries | PBS | 2006 | — | 6 | Comedy |
| Monumental Mysteries | Travel Channel | 2013–2016 | 3 | 39 | Documentary |
| The MoodysMiniseries | Fox | 2019–2021 | — | 6 | Comedy |
| Moolah Beach | Fox Kids | 2001 | — | 6 | Reality |
| Moon Knight | Disney+ | 2022 | 1 | 6 | Superhero |
| Moon Over Miami | ABC | 1993 | 1 | 13 | Sitcom |
| Moonbeam CityAnimated series | Comedy Central | 2015 | 1 | 10 | Animated sitcom |
| MoonDreamers | Syndication | 1986–1987 | — | 16 | — |
| Moonhaven | AMC+ | 2022 | 1 | 6 | — |
| Moonlight | CBS | 2007–2008 | 1 | 16 | Thriller |
| Moonlighting | ABC | 1985–1989 | 5 | 67 | Comedy |
| Moonshiners | Discovery Channel | 2011 | 5 | 67 | Docu-soap |
| Moral Court | Syndication | 2000–2001 | 1 | 410 | — |
| Moral OrelAnimated series | Adult Swim | 2005–2008 | 3 | 43 | Comedy |
| More in Common | ABC Television | 2018–on air | 3 | 58 | — |
| More to Love | Fox | 2009 | 1 | 9 | Reality |
| The Morey Amsterdam Show | CBS | 1949 | 3 | 82 | Sitcom |
| Mork & Mindy | ABC | 1978–1982 | 4 | 95 | Science fiction |
| Mork & Mindy/Laverne & Shirley/Fonz HourAnimated series | ABC | 1982–1983 | 1 | 27 | Comedy |
| Morning CallNews program | CNBC, CNBC Europe | 2005 | — | — | Business |
| Morning Express with Robin Meade | HLN, Sirius XM Rad | 2005–2022 | — | — | News |
| Morning Joe First LookNews program | MS NOW | 2004–2020 | — | — | — |
| Morning Joe Weekend | MS NOW | 2007 | — | — | News |
| The Morning Show | Apple TV | 2019–on air | 4 | 40 | Drama |
| Mornings with Maria | Fox Business | 2014–2015 | — | — | Talk show |
| Mortal Kombat: Conquest | TNT | 1998–1999 | 1 | 22 | Fantasy |
| Mortal Kombat: Defenders of the RealmAnimated series | USA Network | 1996 | 1 | 13 | Fantasy |
| Mortal Kombat: LegacyWeb series | YouTube | 2011–2013 | 2 | 19 | Action |
| The Mortified Sessions | Sundance TV | 2011–2012 | 2 | 16 | — |
| Morton & Hayes | CBS | 1991 | 1 | 6 | Comedy |
| The Morton Downey Jr. Show | WWOR-TV | 1987–1989 | — | — | — |
| MosaicMiniseries | HBO | 2018 | — | 6 | Interactive |
| MosesMiniseries | Rai 1 | 1995 | — | 2 | Drama |
| The Mosquito Coast | Apple TV | 2021–2023 | 2 | 17 | Drama |
| Most Dangerous GameWeb series | Quibi | 2020–on air | — | — | — |
| Most Daring | TruTV | 2007–2010 | 7 | 94 | Reality |
| The Most Deadly Game | ABC | 1970–1971 | 1 | 12 | Drama |
| Most Eligible Dallas | Bravo | 2011 | 1 | 8 | Reality |
| Most Evil | Discovery Channel, Investigation Discovery | 2006 | 2 | 28 | Documentary |
| The Most Extreme | Animal Planet | 2002–2007 | 5 | 77 | Nature documentary |
| Most Outrageous Moments | NBC | 2005–2009 | — | 21 | Reality |
| Most Shocking | | 2006–2010 | 7 | 88 | Reality |
| Most Wanted | ABC | 1976–1977 | 1 | 21 | Detective |
| Mostly 4 Millennials | Adult Swim | 2018 | — | 2 | Comedy |
| Mother Goose and GrimmAnimated series | CBS | 1991–1992 | 2 | 10 | — |
| Mother Goose Stories | Disney Channel, ITV | 1990–2000 | 3 | 39 | Fantasy |
| Mother Up! | Hulu, Citytv | 2013–2014 | 1 | 13 | — |
| Motherland: Fort Salem | Freeform | 2020–2022 | 3 | 30 | Alternate history |
| The Mothers-in-Law | NBC | 1967–1969 | 2 | 56 | Sitcom |
| Motor City Motors | Discovery Channel | 2009 | 1 | 13 | Reality |
| MotorcityAnimated series | Disney XD | 2012–2013 | 1 | 20 | Action |
| MotorWeek | Maryland Public Television | 1981 | 37 | — | — |
| Motorz TV | | 2008 | 6 | 83 | — |
| Motown Live | Fox | 1998–1999 | 1 | 13 | Variety show |
| Motown MagicAnimated series | Netflix | 2018–2019 | — | 25 | Fantasy |
| The Mountain | The WB | 2004–2005 | 1 | 13 | — |
| Mountain Men | History | 2012 | 5 | 55 | Reality |
| Mountain Monsters | Destination America | 2013 | 7 | 61 | Reality |
| Mounted in Alaska | History | 2011 | 1 | 16 | Reality |
| The Mouse and the MonsterAnimated series | UPN | 1996–1997 | 1 | 13 | — |
| The Mouse FactoryAnimated series | | 1972–1973 | 2 | 43 | Children's |
| Mouseterpiece TheaterAnimated series | Disney Channel | 1983 | — | 60 | — |
| The Movie Masters | AMC | 1989–1990 | 1 | — | Panel game |
| Movie Stars | The WB | 1999–2000 | 2 | 21 | Sitcom |
| Movie Surfers | Disney Channel | 1997 | 16 | 44 | — |
| The Movies | CNN | 2019 | 1 | 6 | Documentary |
| The Movies That Made Us | Netflix | 2019–on air | 2 | 8 | Documentary |
| Moville MysteriesAnimated series | Nickelodeon | 2002–2003 | 2 | 26 | Comedy |
| Movin' On | NBC | 1974–1976 | 2 | 45 | — |
| Moving Up | TLC | 2005–2009 | 5 | 62 | Reality |
| Mowgli: The New Adventures of the Jungle Book | Fox | 1998 | 1 | 26 | — |
| The Moxy ShowAnimated series | Cartoon Network | 1993–1995 | — | 24 | Anthology |
| Moyers & Company | Syndication | 2012–2015 | — | 322 | — |
| Mozart in the Jungle | Prime Video | 2014–2018 | 4 | 40 | Comedy-drama |
| Mr. Adams and Eve | CBS | 1957–1958 | 2 | 66 | Sitcom |
| Mr. & Mrs. Smith | CBS | 1996 | 1 | 13 | Comedy-drama |
| Mr. & Mrs. Smith | Prime Video | 2024–on air | 1 | 8 | Action |
| Mr. Belvedere | ABC | 1985–1990 | 6 | 117 | Sitcom |
| Mr. Birchum | | 2024–on air | 1 | 6 | — |
| Mr. BogusAnimated series | Syndication | 1991–1994 | 3 | 58 | Comedy |
| Mr. Box Office | UPN | 2012–2015 | 2 | 36 | Sitcom |
| Mr. Broadway | CBS | 1964 | 1 | 13 | — |
| Mr. Conductor's Thomas Tales | PBS | 1996 | 1 | 6 | — |
| Mr. Corman | Apple TV | 2021 | — | — | Comedy-drama |
| Mr. Deeds Goes to Town | ABC | 1969–1970 | 1 | 17 | Sitcom |
| Mr. Iglesias | Netflix | 2019–2020 | 2 | 21 | Sitcom |
| Mr. Lucky | CBS | 1959–1960 | 1 | 34 | — |
| Mr. Mayor | NBC | 2021–2022 | 2 | 20 | Sitcom |
| Mr. McMahon | Netflix | 2024–on air | 1 | 6 | Documentary |
| Mr. Meaty | Nick at Nite, TeenNick | 2005–2009 | 2 | 20 | Comedy |
| Mr. Mercedes | Audience Network | 2017–2019 | 3 | 22 | Thriller |
| Mr. Merlin | CBS | 1981–1982 | 1 | 22 | Sitcom |
| Mr. Novak | NBC | 1963–1965 | 2 | 60 | — |
| The Mr. Peabody & Sherman Show | Netflix | 2015–2017 | 2 | 26 | Comedy |
| Mr. PicklesAnimated series | Adult Swim | 2014–2019 | 3 | 20 | Comedy |
| The Mr. Potato Head Show | Fox Kids | 1998–1999 | 1 | 13 | — |
| Mr. President | Fox | 1987–1988 | 2 | 24 | Sitcom |
| Mr. Rhodes | NBC | 1996–1997 | 1 | 19 | Sitcom |
| Mr. Robinson | NBC | 2015 | 1 | 6 | Sitcom |
| Mr. Robot | USA Network | 2015–2019 | 4 | 45 | Drama |
| Mr. Romance | Oxygen | 2005 | — | — | Reality |
| Mr. Show with Bob and David | HBO | 1995–1998 | 4 | 32 | Comedy |
| Mr. Smith | NBC | 1983 | 1 | 13 | Sitcom |
| Mr. Smith Goes to Washington | ABC | 1962–1963 | 1 | 25 | Sitcom |
| Mr. Sunshine | ABC | 1986 | 1 | 11 | Sitcom |
| Mr. Sunshine | ABC | 2011 | 1 | 13 | Sitcom |
| Mr. T and Tina | ABC | 1976 | 1 | 9 | Sitcom |
| The Mr. Tenaball Show | Nickelodeon | 1985–1989 | 5 | 250 | Children's |
| Mr. Terrific | CBS | 1967 | 1 | 17 | Sitcom |
| Mr. WongAnimated web series | | 2000 | 1 | 15 | Adult animation |
| Mrs. AmericaMiniseries | FX, Hulu | 2020 | 2 | 9 | Drama |
| Mrs. Columbo | NBC | 1979–1980 | 2 | 13 | Crime |
| Mrs. Davis | Peacock | 2023 | 1 | 8 | Science fiction |
| Mrs. Eastwood & Company | E! | 2012 | 1 | 10 | Reality |
| Mrs. FletcherMiniseries | HBO | 2019 | — | 7 | LGBTQ |
| Ms. Marvel | Disney+ | 2022 | 1 | 6 | Comedy |
| MSNBC Live with Alex Witt | MS NOW | 2017–2018 | — | — | News |
| MSNBC Live with Craig Melvin | MS NOW | 2016–2021 | — | — | — |
| MSNBC ReportsNews program | MS NOW | 1996–2021 | — | 719 | — |
| MTV Cribs | MTV | 2000–2010 | 17 | 106 | Reality |
| MTV Entertainment Studios Presents: Ren & StimpyAnimated series | Comedy Central | 2024–on air | 1 | 10 | Surreal humour |
| MTV Floribama Shore | MTV | 2017 | 1 | 8 | Reality |
| MTV's The 70s House | MTV | 2005 | — | 10 | Reality |
| MTV's Top Pop Group | MTV | 2008 | 1 | 4 | Reality |
| MTV Sports | MTV | 1992–1997 | — | — | — |
| MTV Unplugged | MTV Live, MTV | 1989 | — | — | Music |
| MTV2's Guy Code | MTV2 | 2011–2015 | 5 | 57 | Reality |
| ¡Mucha Lucha!Animated series | The WB, Kids' WB | 2002–2005 | 3 | 52 | — |
| Mud, Sweat & Gears | BBC America | 2015 | 1 | 9 | — |
| Muddling Through | CBS | 1994 | 1 | 10 | Sitcom |
| Mulaney | Fox | 2014–2015 | 1 | 13 | LGBTQ |
| The Mullets | UPN | 2003–2004 | 1 | 11 | Sitcom |
| Mulligan's Stew | NBC | 1977 | 1 | 7 | Sitcom |
| The Mumbly Cartoon ShowAnimated series | ABC | 1976–1977 | 1 | 16 | — |
| Mummies Alive!Animated series | Syndication | 1997 | 1 | 42 | Children's |
| The Mummy: The Animated SeriesAnimated series | Kids' WB | 2001–2003 | 2 | 26 | Action |
| The Munsters | CBS | 1964–1966 | 2 | 70 | Monster |
| The Munsters Today | Syndication | 1988–1991 | 3 | 72 | Sitcom |
| Muppet BabiesAnimated series | CBS | 1984–1996 | 8 | 107 | Sitcom |
| Muppet BabiesAnimated series | Disney Jr. | 2018–2022 | 3 | 89 | — |
| The Muppet Show | ITV | 1976–1981 | 5 | 120 | Variety show |
| The Muppets | ABC | 2015–2016 | 1 | 16 | Sitcom |
| The Muppets: A Celebration of 30 Years | CBS | 1986 | — | — | Crossover |
| The Muppets Mayhem | Disney+, Disney Channel | 2023 | — | 10 | — |
| Muppets Now | Disney+ | 2020 | — | — | — |
| Muppets Tonight | ABC | 1996–1998 | 2 | 22 | Comedy |
| Murdaugh: Death in the Family | Hulu | 2025 | — | — | True crime |
| Murdaugh Murders: A Southern Scandal | Netflix | 2023–on air | 1 | 3 | Documentary |
| Murder | Paramount Network | 2007 | 1 | 10 | Reality |
| Murder Among the Mormons | Netflix | 2021–on air | 1 | 3 | Documentary |
| A Murder at the End of the WorldMiniseries | FX on Hulu | 2023 | 1 | 7 | — |
| Murder DronesAnimated web series | YouTube | 2021–on air | — | — | Post-apocalyptic fiction |
| Murder in Small Town X | Fox | 2001 | 1 | 8 | Reality |
| Murder in the First | TNT | 2014–2016 | 3 | 32 | Crime |
| Murder Mountain | Fusion | 2018–on air | 1 | 6 | Documentary |
| Murder on Middle BeachMiniseries | HBO | 2020 | — | — | Crime |
| Murder One | ABC | 1995–1997 | 2 | 41 | Crime |
| Murder, She Wrote | CBS | 1984–1996 | 12 | 264 | Detective |
| Murderbot | Apple TV | 2025–on air | 1 | 10 | Comedy |
| Murphy Brown | CBS | 1988–1998 | 11 | 260 | Comedy |
| Murphy's Law | ABC | 1988–1989 | 1 | 13 | Detective |
| Muscle | The WB | 1995 | 1 | 13 | Sitcom |
| Muscles & Mayhem: An Unauthorized Story of American Gladiators | Netflix | 2023–on air | 1 | 5 | Documentary |
| The Music Scene | ABC | 1969–1970 | 1 | 17 | — |
| Must Love Cats | Animal Planet | 2011–2012 | 2 | 13 | Documentary |
| Must Love Kids | | 2008 | 1 | 10 | Reality |
| Mutant X | Syndication | 2001–2004 | 3 | 66 | Science fiction |
| Mutt & Stuff | Nick Jr. Channel | 2015–2017 | 2 | 74 | — |
| My 600-lb Life | TLC | 2012 | 4 | 38 | Reality |
| My Antonio | VH1 | 2009 | 1 | 10 | Reality |
| My Big Fat Fabulous Life | TLC | 2015 | 2 | 32 | Reality |
| My Big Fat Greek Life | CBS | 2003 | 1 | 7 | Sitcom |
| My Big Fat Obnoxious Fiance | Fox | 2004 | 3 | 7 | Reality |
| My Big Redneck Wedding | CMT | 2008–2011 | 4 | 41 | Documentary |
| My Boys | TBS | 2006–2010 | 4 | 49 | Sitcom |
| My Brilliant Friend | HBO, Rai 1 | 2018–2024 | 4 | 34 | Drama |
| My Brother and Me | Nickelodeon | 1994–1995 | 1 | 13 | Sitcom |
| My Brother, My Brother and Me | SeeSo | 2017 | 1 | 6 | Comedy |
| My Cat from Hell | Animal Planet | 2011–2018 | 10 | 96 | Reality |
| My Coolest Years | VH1 | 2004–2005 | 1 | 7 | — |
| My Crazy Ex | LMN | 2014–2018 | 5 | 111 | Reality |
| My Dad Is Better Than Your Dad | NBC | 2008 | 1 | 60 | Game show |
| $#*! My Dad Says | CBS | 2010–2011 | 1 | 18 | Sitcom |
| My Dad the Bounty HunterAnimated series | Netflix | 2023–on air | 2 | 20 | Science fiction |
| My Diet Is Better Than Yours | ABC | 2016 | 1 | 8 | Reality |
| My Drunk KitchenWeb series | YouTube | 2011 | 3 | 44 | LGBTQ |
| My Fair Brady | VH1 | 2005–2008 | 3 | 31 | Reality |
| My Family's Got Guts | Nickelodeon | 2008–2009 | 2 | 22 | — |
| My Favorite Martian | CBS | 1963–1966 | 3 | 107 | Science fiction |
| My Favorite MartiansAnimated series | CBS | 1973 | 1 | 16 | — |
| My Feet Are Killing Me | TLC | 2020–on air | 4 | 40 | Documentary |
| My Five Wives | TLC | 2013–2014 | 2 | 21 | Reality |
| My Friend Flicka | CBS | 1956–1957 | 1 | 39 | Western |
| My Friend Tony | NBC | 1969 | 1 | 16 | Comedy |
| My Friends Tigger & PoohAnimated series | Playhouse Disney, Disney Channel | 2007–2010 | 3 | 44 | Comedy |
| My Generation | ABC | 2010 | 1 | 8 | — |
| My Ghost Story | FYI | 2010–2013 | 6 | 75 | — |
| My Giant Life | TLC | 2015–2017 | 1 | 6 | Reality |
| My Guide to Becoming a Rock Star | The WB | 2002 | 1 | 13 | Comedy |
| My Guys | CBS | 1996 | 1 | 6 | — |
| My Gym Partner's a MonkeyAnimated series | Cartoon Network | 2005–2008 | 4 | 52 | Children's |
| My House | Vice TV | 2018 | — | 10 | LGBTQ |
| My Kind of Town | ABC | 2005 | 1 | 4 | — |
| My Kitchen Rules | Fox | 2017 | 1 | 8 | — |
| My Life and Times | ABC | 1991 | 1 | 6 | — |
| My Life as a Teenage RobotAnimated series | Nickelodeon | 2003–2007 | 3 | 40 | Science fiction |
| My Life as Liz | MTV | 2010–2011 | 2 | 21 | Reality |
| My Life is a Lifetime Movie | Lifetime | 2012 | 1 | 7 | Reality |
| My Life with the Walter Boys | Netflix | 2023–on air | 3 | 30 | Teen drama |
| My Little Margie | CBS | 1952–1955 | 4 | 126 | Sitcom |
| My Little PonyAnimated series | Syndication | 1986–1987 | 2 | 65 | Comedy |
| My Little Pony: Friendship Is MagicAnimated series | Hub Network, Discovery Family | 2010–2019 | 9 | 222 | Children's |
| My Little Pony: Pony Life | Discovery Family | 2020–2021 | 2 | 40 | Fantasy |
| My Little Pony TalesAnimated series | Syndication | 1992 | 1 | 26 | — |
| My Living Doll | CBS | 1964–1965 | 1 | 26 | Science fiction |
| My Mother the Car | NBC | 1965–1966 | 1 | 30 | Sitcom |
| My Name Is Earl | NBC | 2005–2009 | 4 | 96 | Sitcom |
| My Next Guest Needs No Introduction With David Letterman | Netflix | 2018–on air | 1 | 4 | Talk show |
| My Nezha and TransformersAnimated series | CCTV-14 Children | 2025–on air | — | 52 | Crossover |
| My Own Worst Enemy | NBC | 2008 | 1 | 9 | Action |
| My Perfect Family | Telemundo | 2018 | — | 94 | Drama |
| My Pet MonsterAnimated series | ABC | 1987 | 1 | 13 | Family |
| My Sister Eileen | CBS | 1960–1961 | 1 | 26 | Sitcom |
| My Sister Sam | CBS | 1986–1988 | 2 | 44 | Sitcom |
| My So-Called Life | ABC | 1994–1995 | 1 | 19 | Drama |
| My Son Jeep | NBC | 1953–1963 | 1 | 11 | Comedy |
| My Strange Addiction | TLC | 2010–2015 | 6 | 50 | Documentary |
| My Super Sweet 16 | MTV | 2005–2017 | 10 | 105 | Reality |
| My Three Sons | ABC | 1960–1972 | 12 | 380 | Sitcom |
| My Two Dads | NBC | 1987–1990 | 3 | 60 | Sitcom |
| My Unorthodox Life | Netflix | 2021–on air | 1 | 9 | Reality |
| My View with Lara Trump | Fox News | 2025–on air | 1 | 3 | News |
| My Wife and Kids | ABC | 2001–2005 | 5 | 123 | Sitcom |
| My Wildest Dreams | Fox | 1995 | 1 | 5 | Sitcom |
| My World and Welcome to It | NBC | 1969–1970 | 1 | 26 | Sitcom |
| Mysteries and Scandals | E! | 1998–2001 | 3 | 152 | — |
| Mysteries at the Castle | Travel Channel | 2014–2016 | 3 | 31 | Documentary |
| Mysteries of Chinatown | ABC | 1949–1950 | — | 48 | — |
| The Mysteries of Laura | NBC | 2014–2016 | 2 | 38 | Comedy-drama |
| Mysteries of the Bible | A&E | 1994–1998 | 5 | 45 | — |
| Mysteries of the Faith | Netflix | 2023–on air | 1 | 4 | Documentary |
| The Mysterious Benedict Society | Disney+ | 2021–2022 | 2 | 16 | Fantasy |
| Mysterious IslandMiniseries | Hallmark Channel | 2005 | — | — | Pirate |
| Mysterious Ways | NBC, Ion Television | 2000–2002 | 2 | 44 | Science fiction |
| Mystery! | PBS | 1980–2006 | 27 | 648 | Anthology |
| Mystery Diagnosis | Discovery Health Channel | 2005–2011 | 10 | 99 | Popularisation of science |
| Mystery Diners | Food Network | 2012–2016 | 11 | 140 | Reality |
| The Mystery Files of Shelby Woo | Nickelodeon | 1996–1998 | 4 | 41 | Detective |
| Mystery Girls | Freeform | 2014 | 1 | 10 | Sitcom |
| Mystery Hunters | YTV | 2002–2009 | 4 | 78 | — |
| Mystery Island | CBS | 1977–1978 | — | 16 | — |
| The Mystery of Natalie WoodMiniseries | ABC | 2004 | — | — | Biographical |
| Mystery of the Senses | PBS | 1995 | — | 5 | Documentary |
| Mystery Science Theater 3000 | Netflix | 1988–1999 | 14 | 211 | Z movie |
| Mystery Woman | Hallmark Channel | 2003–2007 | — | 11 | Drama |
| MysteryQuest | History | 2009 | 1 | 10 | — |
| The Mystic Knights of Tir Na Nog | Fox | 1998–1999 | 1 | 50 | Fantasy |
| MysticonsAnimated series | Nicktoons, Nickelodeon | 2017–2018 | 2 | 40 | Children's |
| Myth Defying with Dr. Holly | Z Living, InTheBoxTV | 2013 | 1 | — | Talk show |
| MythBusters | Discovery Channel | 2003–2018 | 14 | 173 | Factual |
| MythBusters: The Search | Science Channel | 2017 | 1 | 8 | Game show |
| Mythic Quest | Apple TV | 2020–on air | 4 | 40 | Comedy |
| Mythos | PBS | 1999 | 3 | 15 | Documentary |