| I (Almost) Got Away with It | Investigation Discovery | 2010–2016 | 7 | 93 | Documentary |
| I Am Cait | E! | 2015–2016 | 2 | 16 | Reality |
| I Am Frankie | Nickelodeon | 2017–2018 | 2 | 40 | Science fiction |
| I Am Georgina | Netflix | 2022–2023 | 1 | 6 | Documentary |
| I Am GrootAnimated series | Disney+ | 2022–2023 | 2 | 10 | Fantasy |
| I Am Jazz | TLC | 2015 | 8 | 73 | LGBTQ |
| I Am Not Okay With This | Netflix | 2020 | 1 | 7 | Comedy-drama |
| I Am the Greatest: The Adventures of Muhammad AliAnimated series | NBC | 1977 | 1 | 13 | — |
| I Am the NightMiniseries | TNT | 2019 | 1 | 8 | Drama |
| I Am WeaselAnimated series | Cartoon Network | 1997–2000 | 5 | 79 | Comedy |
| I Bet | UPN | 2005 | 1 | 9 | Reality |
| I Bet You | MOJO HD | 2008 | 2 | 24 | Reality |
| I Can Do That | NBC | 2015 | 1 | 6 | — |
| I, Detective | TruTV | 2001–2006 | 5 | 37 | Reality |
| I Didn't Do It | Disney Channel | 2014–2015 | 2 | 39 | Teen sitcom |
| I Dream of Jeannie | NBC | 1965–1970 | 5 | 139 | Sitcom |
| I Dream of NeNe: The Wedding | Bravo | 2013 | 1 | 7 | Reality |
| I Feel Bad | NBC | 2018–on air | — | — | Comedy |
| I Found The Gown | TLC | 2012–2014 | 2 | 22 | Reality |
| I Get That a Lot | Rai 1 | 2009 | 3 | 7 | Reality |
| I Hate My 30's | VH1 | 2007 | 1 | 8 | Sitcom |
| I Hate My Job | Spike TV | 2004–2005 | 1 | 7 | — |
| I Hate My Teenage Daughter | Fox | 2011–2012 | 1 | 13 | Sitcom |
| I Heart Arlo | Netflix | 2021–on air | — | — | — |
| I Just Want My Pants Back | MTV | 2011–2012 | 1 | 12 | Comedy-drama |
| I Kid with Brad Garrett | TLC | 2011 | 1 | 12 | Reality |
| I Know My Kid's a Star | VH1 | 2008 | — | 8 | Reality |
| I Know This Much Is TrueMiniseries | HBO | 2020 | 1 | 6 | — |
| I Know What You Did Last Summer | Prime Video | 2021 | 1 | 8 | Teen drama |
| I'll Be Gone in the DarkMiniseries | HBO | 2020 | — | 6 | True crime |
| I'll Fly Away | NBC, PBS | 1991–1993 | 2 | 38 | Drama |
| I'll Take ManhattanMiniseries | CBS | 1987 | — | 2 | — |
| I Love Dick | Prime Video | 2016–2017 | 1 | 8 | Comedy |
| I Love Jenni | Universo | 2011–2013 | 3 | 37 | Reality |
| I Love Kellie Pickler | CMT | 2015–2017 | 3 | 35 | — |
| I Love LA | HBO | 2025–on air | 1 | 8 | Comedy |
| I Love Lucy | CBS | 1951–1957 | 6 | 181 | Sitcom |
| I Love Money | VH1 | 2008–2010 | 2 | 41 | Reality |
| I Love New York | VH1 | 2007–2008 | 2 | 25 | Reality |
| I Love New York 2 | VH1 | 2007–2008 | — | 13 | Reality |
| I Love the 2000s | VH1 | 2014 | 1 | 10 | — |
| I Love the '70s | VH1 | 2003 | — | 10 | — |
| I Love the '70s: Volume 2 | VH1 | 2006 | 1 | 10 | — |
| I Love the '80s | VH1 | 2002 | 1 | 10 | — |
| I Love the '80s 3-D | VH1 | 2005 | 1 | 10 | — |
| I Love the '80s Strikes Back | VH1 | 2003 | 1 | 10 | — |
| I Love the '90s | VH1 | 2004 | 1 | 10 | — |
| I Love the '90s: Part Deux | VH1 | 2004–2005 | 1 | 10 | — |
| I Love the New Millennium | VH1 | 2008 | 1 | 8 | — |
| I Love You, America with Sarah Silverman | Hulu | 2017–2018 | 1 | 5 | Talk show |
| I Love You, Now Die: The Commonwealth Vs. Michelle CarterMiniseries | HBO | 2019 | — | — | Documentary |
| I'm a Big Girl Now | ABC | 1980–1981 | 1 | 19 | Sitcom |
| I'm Alive | Animal Planet | 2009–2011 | 2 | 21 | — |
| I'm Dickens, He's Fenster | ABC | 1962–1963 | 1 | 32 | Sitcom |
| I'm Dying Up Here | Showtime | 2017–2018 | 2 | 20 | Comedy-drama |
| I'm in the Band | Disney XD | 2009–2011 | 2 | 42 | Music |
| I'm Married to a... | VH1 | 2013 | 1 | 12 | — |
| I'm Sorry | TruTV | 2017 | 2 | 20 | Comedy |
| I'm with Busey | Comedy Central | 2003 | 1 | 13 | — |
| I'm with Her | ABC | 2003–2004 | 1 | 22 | Sitcom |
| I'm with the Band: Nasty Cherry | Netflix | 2019 | 1 | 6 | Reality |
| I Married... | VH1 | 2003–2005 | 1 | 7 | Reality |
| I Married a Mobster | Investigation Discovery | 2011–2012 | 2 | 22 | Documentary |
| I Married Dora | ABC | 1987–1988 | 1 | 13 | Sitcom |
| I Married Joan | NBC | 1952–1955 | 3 | 98 | Sitcom |
| I May Destroy YouMiniseries | BBC One | 2020 | 1 | 12 | Comedy-drama |
| I Pity the Fool | TV Land | 2006 | — | 6 | Reality |
| I Shouldn't Be Alive | Discovery Channel, Animal Planet | 2005–2012 | 5 | 58 | Documentary |
| I Spy | NBC | 1965–1968 | 3 | 82 | Comedy-drama |
| I Survived... | FYI | 2008–2015 | 6 | 115 | Documentary |
| I Survived a Japanese Game Show | ABC | 2008–2009 | 2 | 15 | Reality |
| I Think You Should Leave with Tim Robinson | Netflix | 2019–on air | 3 | 18 | Sketch comedy |
| I Used to Be Fat | MTV | 2010–2013 | 2 | 28 | — |
| I've Got a Secret | CBS | 2006 | — | 2,006 | Panel game |
| I Wanna Marry "Harry" | Fox | 2014 | 1 | 8 | — |
| I Want a Famous Face | MTV | 2004–2005 | 1 | 12 | Reality |
| I Want to Work for Diddy | VH1 | 2008–2010 | 2 | 20 | Reality |
| I Will Find You | Netflix | 2026 | 1 | 8 | Crime drama |
| iCarly | Nickelodeon | 2007–2012 | 7 | 97 | Teen sitcom |
| iCarly | Paramount+ | 2021–2023 | 3 | 33 | Sitcom |
| Ice | Audience Network | 2016–2018 | 2 | 20 | Drama |
| Ice Age: Scrat TalesAnimated series | Disney Channel, Disney+ | 2022–on air | 1 | 6 | — |
| Ice & Coco | Syndication | 2015 | 1 | 15 | — |
| Ice Cold Gold | Animal Planet | 2013–2015 | 3 | 28 | Reality |
| Ice Loves Coco | E! | 2011–2013 | 3 | 28 | Reality |
| Ice Road Truckers | History | 2007–2017 | 11 | 138 | Reality |
| Ice-T's Rap School | VH1 | 2005–2006 | — | 6 | Reality |
| Ichabod and Me | CBS | 1961–1962 | 1 | 36 | Sitcom |
| Iconoclasts | Sundance TV | 2005–2012 | 6 | 36 | Documentary |
| Icons | G4 | 2002–2007 | 5 | 88 | — |
| Identity | NBC | 2006–2007 | — | 12 | Game show |
| The Idiot Box | MTV | 1990–1991 | 1 | 6 | — |
| Idiotest | Game Show Network | 2014–2017 | 3 | 105 | Game show |
| Idiotsitter | Comedy Central | 2016–2017 | — | 10 | Sitcom |
| Iditarod: Toughest Race on Earth | Discovery Channel | 2008 | 1 | 6 | Reality |
| The Idol | HBO | 2023 | 1 | 5 | Drama |
| If I Can DreamWeb series | | 2010 | 1 | 32 | — |
| If Loving You Is Wrong | OWN | 2014–2020 | 2 | 42 | Soap opera |
| If Not for You | CBS | 1995 | 1 | 7 | Sitcom |
| If Tomorrow ComesMiniseries | CBS | 1986 | 1 | 3 | — |
| If Walls Could Talk | TLC | 1998–2008 | 20 | 273 | — |
| If You Really Knew Me | MTV | 2010 | 1 | 12 | Reality |
| The IFC Media Project | IFC | 2008–2010 | 3 | 6 | Documentary |
| The Igor Cassini Show | DuMont | 1953–1954 | 1 | 19 | Talk show |
| The Iliza Shlesinger Sketch Show | Netflix | 2020–on air | — | — | — |
| Illinois Instant Riches | WGN-TV, Syndication | 1994–1998 | 4 | — | Game show |
| The Ilona Massey Show | DuMont | 1954–1955 | 1 | 10 | Variety show |
| Imaginary BitchesWeb series | | 2008 | — | 13 | — |
| Imaginary Mary | ABC | 2017 | 1 | 9 | Sitcom |
| Imagination Movers | Disney Channel | 2008–2013 | 3 | 75 | Children's |
| Imagine That | NBC | 2002 | 1 | 6 | Sitcom |
| The Immortal | ABC | 1969–1971 | 1 | 16 | Science fiction |
| Impact! Xplosion | Bally Sports Sun, Challenge | 2002–2021 | — | 662 | — |
| Impastor | TV Land | 2015–2016 | 2 | 20 | Comedy |
| The Imperfects | Netflix | 2022 | 1 | 10 | Science fiction |
| Important Things with Demetri Martin | Comedy Central | 2009–2010 | 2 | 17 | — |
| The ImpossiblesAnimated series | CBS | 1966–1967 | 1 | 18 | — |
| Imposters | Bravo | 2017–2018 | 2 | 20 | LGBTQ |
| Impractical Jokers | TruTV | 2011 | 12 | 287 | Comedy |
| Impulse | YouTube Premium | 2018–2019 | 2 | 20 | Science fiction |
| Imus in the MorningNews program | WFAN, MS NOW | 1996–2018 | — | — | Talk show |
| In a Heartbeat | Disney Channel | 2000–2001 | 1 | 21 | Drama |
| In an Instant | ABC | 2015 | 1 | 7 | Documentary |
| In Case of Emergency | ABC | 2007 | 1 | 13 | Sitcom |
| In Concert | ABC | 1972 | — | — | — |
| In From the Cold | Netflix | 2022–on air | 1 | 8 | Thriller |
| In Harm's Way | The CW | 2008 | — | 8 | Reality |
| In Justice | ABC | 2006 | 1 | 13 | Drama |
| In-Laws | NBC | 2002–2003 | 1 | 15 | Sitcom |
| In Living Color | Fox | 1990–1994 | 5 | 127 | Variety show |
| In Plain Sight | USA Network | 2008–2012 | 5 | 61 | Drama |
| In Search of... | Syndication | 1977 | 6 | 144 | Infotainment |
| In the Beginning | CBS | 1978 | 1 | 9 | Sitcom |
| In the BeginningMiniseries | NBC | 2000 | — | 2 | Drama |
| In The Cut | Bounce TV | 2015 | 1 | 6 | — |
| In the Dark | The CW | 2019–2022 | 4 | 52 | LGBTQ |
| In the Flow with Affion Crockett | Fox | 2011 | 1 | 6 | — |
| In the Heat of the Night | NBC, CBS | 1988–1995 | 8 | 146 | Drama |
| In the House | NBC, UPN | 1995–1999 | 5 | 76 | Sitcom |
| In the Kelvinator Kitchen | NBC | 1947–1948 | — | — | — |
| In the Life | PBS | 1992–2012 | 20 | 197 | LGBTQ |
| In the Motherhood | ABC | 2009 | 1 | 7 | Sitcom |
| In the Womb | National Geographic | 2005–2007 | — | 7 | Documentary |
| In Treatment | HBO | 2008–2021 | 4 | 130 | Drama |
| The InBetween | NBC | 2019 | — | 10 | Drama |
| The Inbetweeners | MTV | 2012 | 1 | 12 | Teen sitcom |
| Inch High, Private EyeAnimated series | NBC | 1973–1974 | 1 | 13 | Comedy |
| Inconceivable | NBC | 2005 | 1 | 9 | Drama |
| Incorporated | Syfy | 2016–2017 | 1 | 10 | Drama |
| The Increasingly Poor Decisions of Todd Margaret | IFC | 2010–2016 | 3 | 18 | Sitcom |
| Incredible Crew | Cartoon Network | 2012 | 1 | 13 | — |
| The Incredible Dr. Pol | Nat Geo Wild | 2011–2024 | 21 | 200 | Docu-soap |
| The Incredible Hulk | CBS | 1978–1982 | 5 | 82 | Drama |
| The Incredible HulkAnimated series | NBC | 1982–1983 | 1 | 13 | Science fiction |
| The Incredible HulkAnimated series | UPN | 1996–1997 | 2 | 21 | Superhero |
| Independent Lens | PBS | 1999 | 13 | 306 | Documentary |
| Independent Network News (US) | Syndication | 1980–1990 | 10 | — | News |
| Indian Matchmaking | Netflix | 2020–on air | 1 | 8 | Documentary |
| Inedible To Incredible | TLC | 2010 | 1 | 6 | Reality |
| The Infinite Worlds of H. G. WellsMiniseries | Hallmark Channel | 2001 | 1 | 6 | Science fiction |
| Infinity TrainAnimated series | Adult Swim, HBO Max | 2019–2021 | 4 | 40 | Fantasy |
| InfomercialsWeb series | Adult Swim | 2009 | 2 | 15 | Short |
| Inhumanoids | Syndication | 1986 | — | 13 | Science fiction |
| Inhumans | ABC | 2017 | 1 | 8 | Action |
| Ink | CBS | 1996–1997 | 1 | 22 | Sitcom |
| Ink Master | Spike TV | 2012 | 15 | 206 | Reality |
| The Innocent Man | Netflix | 2018 | 1 | 6 | True crime |
| The InquiryMiniseries | Rai 1 | 2007 | — | 2 | Historical |
| Inquizition | Game Show Network | 1998–2001 | 3 | — | — |
| Insane Coaster Wars | Travel Channel | 2012–2014 | 3 | 21 | Documentary |
| Insatiable | Netflix | 2018–2019 | 2 | 22 | Black comedy |
| Insecure | HBO | 2016–2021 | 5 | 44 | Comedy-drama |
| The Inside | Fox | 2005 | 1 | 13 | Police procedural |
| Inside Amy Schumer | Comedy Central, Paramount+ | 2013–2016 | 5 | 44 | Sketch comedy |
| Inside Bill's Brain: Decoding Bill GatesMiniseries | Netflix | 2019 | 1 | 3 | Documentary |
| Inside Comedy | Showtime | 2012–2015 | 4 | 36 | Comedy |
| Inside Dish | Food Network | 2004–2005 | 1 | 19 | Cooking show |
| Inside EditionNews program | Syndication, KBS Prime | 1989 | 30 | 11,257 | Entertainment journalism |
| Inside Edition WeekendNews program | Syndication | 1989 | 34 | 11,257 | News magazine |
| Inside Job | TNT | 2014 | 1 | 6 | Reality |
| Inside JobAnimated series | Netflix | 2021–2022 | 2 | 18 | Comedy |
| Inside MMA | AXS TV | 2007–2016 | 10 | — | — |
| Inside/Out | PBS | 1972 | — | 30 | Drama |
| Inside Politics with Dana Bash | CNN | 1993–2005 | — | — | Drama |
| Inside Schwartz | NBC | 2001–2002 | 1 | 13 | Sitcom |
| Inside the Actors Studio | Bravo, Ovation | 1994 | 23 | 277 | Talk show |
| Inside the Mafia | National Geographic Channel | 2005 | 1 | 4 | Crime |
| Inside the NFL | HBO | 1977–2023 | — | — | American football |
| Inside the Vault | WGN America | 2011 | 1 | 10 | — |
| Inside West Coast Customs | Discovery Channel | 2011–2018 | 5 | 53 | — |
| The InsiderNews program | Syndication, CBS | 2004–2017 | 11 | 3,221 | News magazine |
| The Insiders | ABC | 1985–1986 | 1 | 13 | Detective |
| Insomniac with Dave Attell | Comedy Central | 2001–2004 | 4 | 45 | — |
| Inspector GadgetAnimated series | Syndication, France 3 | 1983–1985 | 4 | 86 | Crime |
| Inspector GadgetAnimated series | Cartoon Network, Boomerang | 2015–2018 | 4 | 52 | Adventure |
| Inspector Gadget's Field Trip | | 1996–1998 | 2 | 26 | Comedy |
| Inspector Mom | Lifetime | 2006–2007 | 1 | 11 | — |
| The Inspectors | CBS | 2015–2019 | 3 | 63 | — |
| Instant Mom | Nick at Nite, Nickelodeon | 2013–2015 | 3 | 65 | Sitcom |
| Instant Recall | Game Show Network | 2010 | 1 | 8 | — |
| INSTIИCT | CBS | 2018–2019 | 2 | 13 | LGBTQ |
| The Institute | MGM+ | 2025–on air | 1 | 8 | Science fiction |
| Intelligence | CBS | 2014 | 1 | 13 | Science fiction |
| Interior Chinatown | Hulu | 2024–on air | 1 | 10 | Drama |
| Interior Therapy with Jeff Lewis | Bravo | 2012–2013 | 2 | 20 | Reality |
| InterloperWeb series | | 2026–on air | — | — | — |
| The Internet Ruined My Life | Syfy | 2016 | 1 | 6 | — |
| The Interns | CBS | 1970–1971 | 1 | 24 | — |
| Interpol Investigates | National Geographic | 2004–2005 | 1 | 12 | — |
| Interrogation | Paramount+ | 2020 | 1 | 10 | Drama |
| Intervention | A&E | 2005 | 14 | 194 | Reality |
| Intervention: Codependent | LMN | 2016 | — | — | Documentary |
| Interview with the Vampire | AMC | 2022–on air | 3 | 22 | Vampire |
| Intimate Portrait | Lifetime | 1994–2005 | 12 | 271 | Biographical |
| Into the Badlands | AMC | 2015–2019 | 3 | 32 | Post-apocalyptic |
| Into the Dark | Hulu | 2018–2021 | 2 | 24 | Horror |
| Into the Unknown: Making Frozen 2 | Disney+ | 2020–on air | 1 | 6 | — |
| Into the WestMiniseries | TNT | 2005 | 1 | 6 | Western |
| Intricate Vengeance | YouTube | 2016 | — | — | Crime |
| IntrudersMiniseries | CBS | 1992 | — | 1 | — |
| Intruders | BBC America | 2014 | 1 | 8 | Drama |
| Invader ZimAnimated series | Nickelodeon | 2001–2006 | 2 | 27 | Comedy |
| The Invaders | ABC | 1967–1968 | 2 | 43 | Science fiction |
| The InvadersMiniseries | Fox | 1995 | — | 2 | Science fiction |
| InvasionMiniseries | NBC | 1997 | — | 2 | Thriller |
| Invasion | ABC | 2005–2006 | 1 | 22 | Science fiction |
| Invasion | Apple TV | 2021–on air | 3 | 30 | Science fiction |
| Invasion AmericaAnimated series | The WB | 1998 | 1 | 13 | Science fiction |
| Invasion Iowa | | 2005 | 1 | 4 | Reality |
| Inventing Anna | Netflix | 2022 | 1 | 9 | Drama |
| Invention USA | History | 2011–2012 | 2 | 14 | Reality |
| The Investigators | CBS | 1961 | 1 | 13 | Adventure |
| InvincibleAnimated series | Prime Video | 2021–on air | 4 | 33 | Adult animation |
| The Invisible Man | NBC | 1975–1976 | 1 | 13 | Science fiction |
| The Invisible Man | Syfy | 2000–2002 | 2 | 46 | Science fiction |
| Irma VepMiniseries | HBO | 2022 | — | 8 | Drama |
| Iron Chef America | Food Network | 2005–2018 | 11 | 205 | — |
| Iron Chef USA | UPN | 2001 | — | 2 | — |
| The Iron Horse | ABC | 1966–1968 | 2 | 47 | Western |
| Iron ManAnimated series | Syndication | 1994–1996 | 2 | 26 | Superhero |
| Iron Man and His Awesome FriendsAnimated series | Disney Jr. | 2025–on air | 1 | 19 | — |
| Iron Man: Armored AdventuresAnimated series | France 4 | 2009–2012 | 2 | 52 | Superhero |
| Iron Ring | | 2008 | — | 14 | Reality |
| Ironheart | Disney+ | 2025–on air | — | 6 | Superhero |
| Ironside | NBC | 1967–1975 | 8 | 199 | Crime |
| Ironside | NBC | 2013 | 1 | 9 | Police procedural |
| The Irrational | NBC | 2023–2025 | 2 | 29 | — |
| Is It Cake? | Netflix | 2022–on air | 3 | 24 | Reality |
| Is It Real? | National Geographic | 2005–2007 | 2 | 28 | Documentary |
| Ishq o'yinlari | Sevimli TV | 2020–2021 | 1 | 48 | Drama |
| Island Son | CBS | 1989–1990 | 1 | 18 | Crime |
| The Islanders | ABC | 1960–1961 | — | 24 | — |
| IslandsMiniseries | Cartoon Network | 2017 | — | 8 | — |
| ItMiniseries | ABC | 1990 | 1 | 2 | Horror |
| It Could Happen Tomorrow | The Weather Channel | 2006–2007 | — | 33 | — |
| The It Factor | Bravo | 2002–2003 | 2 | — | Reality |
| It Had to Be You | CBS | 1993 | 1 | 9 | Sitcom |
| It Is Written | Trinity Broadcasting Network, Three Angels Broadcasting Network | 1956–2015 | — | 50 | — |
| It Only Hurts When I Laugh | TruTV | 2009–2011 | 3 | 38 | Serial |
| It Pays to Be Ignorant | CBS, NBC | 1949–1974 | 3 | — | — |
| It's a Big Big World | PBS Kids, PBS | 2006–2010 | 2 | 47 | — |
| It's a Brad, Brad World | Bravo | 2012–2013 | 2 | 16 | Documentary |
| It's a Business | DuMont | 1952 | 1 | 10 | Sitcom |
| It's a Great Life | NBC | 1954–1956 | 2 | 78 | Sitcom |
| It's a Living | ABC, Syndication | 1980–1989 | 6 | 120 | Sitcom |
| It's a Man's World | NBC | 1962–1963 | 1 | 19 | Comedy-drama |
| It's a Miracle | Ion Television | 1998–2004 | 6 | 243 | — |
| It's About Time | CBS | 1966–1967 | 1 | 26 | Science fiction |
| It's All Geek to Me | | 2007 | 1 | 12 | — |
| It's All Relative | ABC | 2003–2004 | 1 | 22 | Comedy |
| It's Always Sunny in Philadelphia | FXX, FX | 2005 | 17 | 178 | Sitcom |
| It's Bruno! | Netflix | 2019–on air | 1 | 8 | Comedy-drama |
| It's Effin' Science | G4 | 2010 | 1 | 10 | Reality |
| It's Garry Shandling's Show | Showtime | 1986–1990 | 4 | 72 | Sitcom |
| It's Like, You Know... | ABC | 1999–2000 | 2 | 25 | Sitcom |
| It's Me or the Dog | Animal Planet | 2008–2012 | 4 | 77 | Reality |
| It's News to Me | CBS | 1951–1954 | 3 | 17 | Panel game |
| It's Not Easy | ABC | 1983 | 1 | 10 | Sitcom |
| It's Not You, It's Men | OWN | 2016 | 1 | 8 | — |
| It's On with Alexa Chung | MTV | 2009 | 2 | 24 | — |
| It's Punky BrewsterAnimated series | NBC | 1985–1986 | 2 | 26 | Comedy |
| It's Worth What? | NBC | 2011 | 1 | 9 | Reality |
| It's Your Bet | Syndication | 1969–1973 | 4 | 196 | — |
| It's Your Chance of a Lifetime | Fox | 2000 | 1 | 5 | Game show |
| It's Your Move | NBC | 1984–1985 | 1 | 18 | Teen sitcom |
| It Takes a Church | Game Show Network | 2014–2015 | 2 | 16 | Game show |
| It Takes a Thief | ABC | 1968–1970 | 3 | 66 | Action-adventure |
| It Takes a Thief | Discovery Channel | 2005–2007 | 2 | 80 | Reality |
| It Takes Two | NBC, Freeform | 1969–1997 | — | — | — |
| It Takes Two | ABC | 1982–1983 | 1 | 22 | Sitcom |
| It: Welcome to Derry | HBO Max, HBO | 2025–on air | 1 | 8 | Horror |
| Itsy Bitsy SpiderAnimated series | USA Network | 1994–1996 | 2 | 26 | Fantasy |
| Ivan the Terrible | CBS | 1976 | 1 | 5 | Sitcom |
| IwájúAnimated series | Disney+ | 2024 | 1 | 6 | Science fiction |
| Iyanla: Fix My Life | OWN | 2012–2019 | 5 | 56 | Reality |
| iZombie | The CW | 2015–2019 | 5 | 71 | Zombie |