| Regular Show: The Lost TapesAnimated series | 2026–on air | — | — | Comedy | J. G. Quintel |
| Jessica's Big Little WorldAnimated series | 2023–2024 | 1 | 20 | Children's | |
| Lu & the Bally BunchAnimated series | 2023 | 1 | 76 | Children's | |
| BatwheelsAnimated series | 2022–on air | 3 | 93 | Children's | |
| Bugs Bunny BuildersAnimated series | 2022–on air | 2 | — | Children's | |
| We Baby BearsAnimated series | 2022–on air | 2 | 47 | Fantasy | |
| Harry Potter: Hogwarts Tournament of HousesGame show | 2021 | 1 | 4 | — | |
| Thomas & Friends: All Engines GoAnimated series | 2021–on air | 4 | 148 | Children's | Britt Allcroft |
| ThunderCats RoarAnimated series | 2020 | 1 | 52 | Science fantasy | |
| Care Bears: Unlock the MagicAnimated series | 2019–on air | 2 | 55 | Children's | |
| DC Super Hero GirlsAnimated series | 2019 | 2 | 78 | Action | |
| Lazor WulfAnimated series | 2019–2021 | — | — | Comedy | |
| Mao Mao: Heroes of Pure HeartAnimated series | 2019–2020 | 1 | 40 | Fantasy | Parker Simmons |
| Power PlayersAnimated series | 2019–on air | 1 | 78 | Science fiction | |
| Scooby-Doo and Guess Who?Animated series | 2019–2021 | 2 | 26 | Comedy | |
| Steven Universe FutureAnimated series | 2019–2020 | 1 | 20 | Comedy-drama | Rebecca Sugar |
| Victor and ValentinoAnimated series | 2019–2022 | 3 | 68 | Mystery | |
| Apple & OnionAnimated series | 2018–2021 | 2 | 76 | Comedy | |
| Craig of the CreekAnimated series | 2018–2025 | 6 | 180 | Children's | |
| Mega Man: Fully ChargedAnimated series | 2018–2019 | — | 26 | — | |
| Summer Camp IslandAnimated series | 2018–2023 | 6 | 120 | Adventure | Julia Pott |
| Transformers: CyberverseAnimated series | 2018–2020 | 2 | 62 | Comedy | |
| Cloudy with a Chance of Meatballs: The SeriesAnimated series | 2017–2018 | 2 | 104 | Comedy | |
| Dorothy and The Wizard of OzAnimated series | 2017–2020 | 3 | 60 | Fantasy | |
| IslandsMiniseries | 2017 | — | 8 | — | |
| OK K.O.! Let's Be HeroesAnimated series | 2017–2019 | 3 | 112 | Comedy | |
| Unikitty!Animated series | 2017–2020 | 3 | 104 | Fantasy | |
| Ben 10Animated series | 2016–2021 | 4 | 166 | Science fiction | Man of Action Studios |
| Brad Neely's Harg Nallin' Sclopio PeepioAnimated series | 2016 | 1 | 10 | Sketch | Brad Neely |
| BunniculaAnimated series | 2016–2018 | 1 | 104 | — | |
| Justice League: ActionAnimated series | 2016–2018 | 1 | 52 | Children's | |
| Mighty MagiswordsAnimated web series | 2016–2019 | 2 | 92 | — | |
| The Powerpuff GirlsAnimated series | 2016–2019 | 3 | 119 | Fantasy | Bob Boyle, Nick Jennings |
| Be Cool, Scooby-Doo!Animated series | 2015–2018 | 2 | 52 | Comedy | |
| Inspector GadgetAnimated series | 2015–2018 | 4 | 52 | Adventure | |
| Lego Nexo KnightsAnimated series | 2015–2018 | 4 | 40 | Knight | |
| Neon Joe, Werewolf Hunter | 2015–2017 | 1 | 5 | — | |
| New Looney TunesAnimated series | 2015–2019 | 3 | 102 | Comedy | |
| The Jack and Triumph Show | 2015 | 1 | 7 | — | |
| Transformers: Robots in DisguiseAnimated series | 2015–2017 | 3 | 71 | Comedy | |
| We Bare BearsAnimated series | 2015–2019 | 4 | 140 | Children's | Daniel Chong |
| ClarenceAnimated series | 2014–2018 | 3 | 130 | Comedy | |
| Decker | 2014–2020 | 1 | 6 | Sitcom | |
| Long Live the RoyalsMiniseries | 2014–2015 | 1 | 4 | Animated sitcom | |
| Mike Tyson MysteriesAnimated series | 2014–2020 | 2 | 30 | Comedy | |
| MixelsAnimated series | 2014–2016 | 3 | 31 | Comedy | |
| Over the Garden WallMiniseries | 2014–2019 | 1 | 10 | Mystery | Patrick McHale |
| Sonic BoomAnimated series | 2014–2017 | 2 | 104 | Adventure | |
| The Tom and Jerry ShowAnimated series | 2014–2021 | 5 | 117 | Comedy | William Hanna |
| Tim & Eric's Bedtime Stories | 2014–2017 | 2 | 13 | Anthology | |
| Beware the BatmanAnimated series | 2013–2014 | 1 | 26 | Comedy | Glen Murakami |
| Newsreaders | 2013–2015 | 2 | 24 | Comedy | Rob Corddry |
| Steven UniverseAnimated series | 2013–2019 | 5 | 108 | Science fiction | Rebecca Sugar |
| Tales of MetropolisMiniseries | 2013 | 1 | 3 | Comedy | |
| Teen Titans Go!Animated series | 2013 | 9 | 441 | Children's | Aaron Horvath, Michael Jelenic |
| Uncle GrandpaAnimated series | 2013–2017 | 5 | 156 | Fantasy | Peter Browngardt |
| Action Dad | 2012 | 1 | 22 | Action | |
| Ben 10: Omniverse television seriesAnimated series | 2012–2014 | 4 | 80 | Children's | |
| Black DynamiteAnimated series | 2012–2015 | 2 | 20 | Comedy | |
| DC Nation | 2012–2014 | 2 | 104 | — | Malcolm Wheeler-Nicholson |
| DragonsAnimated series | 2012–2018 | 8 | 118 | Fantasy | |
| Incredible Crew | 2012 | 1 | 13 | — | Nick Cannon |
| Level Up | 2012–2013 | 2 | 35 | — | |
| Loiter Squad | 2012–2014 | 2 | 21 | — | |
| Super Best Friends ForeverMiniseries | 2012 | 1 | 5 | Action | Lauren Faust |
| The Eric Andre Show | 2012 | 4 | 40 | Comedy | Eric André |
| The High Fructose Adventures of the Annoying Orange | 2012–2014 | 2 | 52 | Live action & animation | |
| China, ILAnimated series | 2011–2015 | 3 | 30 | College life | |
| DC Nation ShortsAnimated series | 2011–2014 | — | 164 | Comedy | |
| DC's World's FunnestMiniseries | 2011–2014 | 1 | 10 | Comedy | |
| Green Lantern: The Animated SeriesAnimated series | 2011–2013 | 1 | 26 | Action | Bruce Timm |
| Mongo Wrestling AllianceAnimated series | 2011 | 1 | 10 | Adult animation | |
| NTSF:SD:SUV:: | 2011–2013 | 3 | 39 | Black comedy | |
| NinjagoAnimated series | 2011–2022 | 15 | 160 | — | Michael Hegner |
| Secret Mountain Fort AwesomeAnimated series | 2011–2012 | 2 | 26 | Fantasy | Peter Browngardt |
| The Amazing World of GumballAnimated series | 2011–2019 | 7 | 240 | Satire | Ben Bocquelet |
| The Heart, She Holler | 2011–2014 | 3 | 28 | Black comedy | Vernon Chatman, John Lee |
| The Looney Tunes ShowAnimated series | 2011–2013 | 2 | 52 | Children's | Sam Register |
| The Problem SolverzAnimated series | 2011–2013 | 2 | 26 | Comedy | |
| ThundercatsAnimated series | 2011–2012 | 1 | 26 | Fantasy | Ted Wolf |
| Adventure TimeAnimated series | 2010–2018 | 10 | 278 | Post-apocalyptic | Pendleton Ward |
| Ben 10: Ultimate AlienAnimated series | 2010–2012 | 3 | 52 | Fantasy | Man of Action Studios |
| Generator RexAnimated series | 2010–2013 | 3 | 60 | Superhero | Man of Action Studios |
| Hero FactoryAnimated series | 2010–2014 | 4 | 11 | Children's | |
| Hero: 108Animated series | 2010–2012 | 2 | 52 | Comedy | |
| MadAnimated series | 2010–2013 | 4 | 103 | Comedy | Kevin Shinick |
| Mary Shelley's FrankenholeAnimated series | 2010–2012 | 2 | 20 | Comedy | Dino Stamatopoulos |
| Pink Panther and PalsAnimated series | 2010–2012 | 1 | 26 | Children's | |
| Regular ShowAnimated series | 2010–2017 | 8 | 261 | Children's | J. G. Quintel |
| RobotomyAnimated series | 2010–2011 | 1 | 10 | Comedy | |
| Scooby-Doo! Mystery IncorporatedAnimated series | 2010–2013 | 2 | 52 | Fantasy | Ken Spears, Joe Ruby |
| Sym-Bionic TitanAnimated series | 2010–2011 | 1 | 20 | Science fiction | Genndy Tartakovsky, Paul Rudish |
| Unnatural History | 2010 | 1 | 13 | — | Mike Werb |
| Young JusticeAnimated series | 2010–2022 | 4 | 98 | Drama | Brandon Vietti, Greg Weisman |
| Bobb'e Says | 2009 | 1 | 6 | — | |
| BrainRush | 2009 | 1 | 6 | — | |
| Casper's Scare SchoolAnimated series | 2009–2012 | 3 | 54 | Comedy | |
| Destroy Build Destroy | 2009–2011 | 4 | 37 | — | |
| Dude, What Would Happen | 2009–2011 | 4 | 37 | — | |
| Hot Wheels: Battle Force 5Animated series | 2009–2011 | 3 | 54 | Comedy | |
| The Super Hero Squad ShowAnimated series | 2009–2011 | 2 | 52 | Comedy | Stan Lee |
| Titan MaximumAnimated series | 2009 | — | 72 | — | Matthew Senreich |
| Batman: The Brave and the BoldAnimated series | 2008–2011 | 3 | 65 | Fantasy | |
| Ben 10: Alien ForceAnimated series | 2008–2010 | 3 | 46 | Children's | Man of Action Studios |
| Hole in the Wall | 2008–2009 | — | — | Game show | |
| Star WarsAnimated series | 2008–2020 | 7 | 133 | Fantasy | George Lucas |
| TWF - Thumb Wrestling Federation | 2008–2009 | 5 | 92 | Parody | Larry Schwarz |
| The Marvelous Misadventures of FlapjackAnimated series | 2008–2010 | 3 | 46 | Children's | Thurop Van Orman |
| The Secret SaturdaysAnimated series | 2008–2010 | 2 | 36 | Adventure | Jay Stephens |
| ChowderAnimated series | 2007–2010 | 3 | 49 | Fantasy | C. H. Greenblatt |
| George of the JungleAnimated series | 2007–2017 | 2 | 52 | Comedy | Jay Ward |
| Rick & Steve: The Happiest Gay Couple in All the WorldAnimated series | 2007–2009 | 2 | 14 | Brickfilm | Q. Allan Brocka |
| Storm HawksAnimated series | 2007–2009 | 2 | 52 | Science fiction | Asaph Fipke |
| The Land Before TimeAnimated series | 2007–2008 | 1 | 26 | Comedy | Tony Geiss, Charles Grosvenor |
| The Othersiders | 2007–2009 | 2 | 23 | — | |
| Tim and Eric Awesome Show, Great Job! | 2007–2010 | 5 | 50 | Sketch comedy | Tim Heidecker |
| Transformers: AnimatedAnimated series | 2007–2009 | 3 | 42 | Science fiction | Hasbro |
| Xavier: Renegade AngelAnimated series | 2007–2009 | 2 | 20 | Adult animation | Vernon Chatman, John Lee |
| Assy McGeeAnimated series | 2006–2008 | 2 | 20 | Detective | Matt Harrigan |
| Class of 3000Animated series | 2006–2008 | 2 | 28 | — | |
| Ellen's Acres | 2006–2007 | — | 52 | — | Larry Schwarz |
| Fantastic Four: World's Greatest HeroesAnimated series | 2006–2007 | 1 | 26 | Action | |
| MetalocalypseAnimated series | 2006–2013 | 4 | 63 | Music | Tommy Blacha, Brendon Small |
| Squirrel BoyAnimated series | 2006–2007 | 2 | 52 | Animated sitcom | Everett Peck |
| 12 oz. MouseAnimated series | 2005–2018 | 3 | 22 | Exploitation | Matt Maiellaro |
| Ben 10Animated series | 2005–2008 | 4 | 52 | Fantasy | Man of Action Studios |
| Camp LazloAnimated series | 2005–2008 | 5 | 61 | Children's | Joe Murray |
| Firehouse TalesAnimated series | 2005–2006 | 1 | 26 | Children's | |
| Gerald McBoing-Boing | 2005–2007 | 1 | 52 | — | Dr. Seuss |
| Johnny TestAnimated series | 2005–2014 | 6 | 117 | Children's | Scott Fellows |
| Krypto the SuperdogAnimated series | 2005–2006 | 2 | 39 | — | |
| Lucy, the Daughter of the DevilAnimated series | 2005–2007 | 1 | 11 | Adult animation | Loren Bouchard |
| My Gym Partner's a MonkeyAnimated series | 2005–2008 | 4 | 52 | Children's | Julie McNally-Cahill |
| Pet AlienAnimated series | 2005 | 2 | 52 | Comedy | Jeff Muncy |
| Sunday Pants | 2005 | 1 | 7 | — | |
| The Life & Times of Juniper LeeAnimated series | 2005–2007 | 3 | 40 | Action | Judd Winick |
| Foster's Home for Imaginary FriendsAnimated series | 2004–2009 | 6 | 79 | Fantasy | Craig McCracken |
| Hi Hi Puffy AmiYumiAnimated series | 2004–2006 | 3 | 39 | Comedy anime and manga | Sam Register |
| Justice League UnlimitedAnimated series | 2004–2006 | 3 | 39 | Science fiction | Paul Dini |
| Tom Goes to the MayorAnimated series | 2004–2006 | 2 | 31 | Adult animation | Tim Heidecker |
| Duck DodgersAnimated series | 2003–2005 | 3 | 39 | Children's | |
| Evil Con CarneAnimated series | 2003–2004 | 2 | 14 | Science fiction comedy | Maxwell Atoms |
| Star WarsAnimated series | 2003–2005 | 3 | 25 | Fantasy | Genndy Tartakovsky |
| Teen TitansAnimated series | 2003–2006 | 5 | 65 | Children's | Glen Murakami |
| The Venture Bros.Animated series | 2003–2018 | 7 | 81 | Comedy | Doc Hammer, Christopher McCulloch |
| Yakkity YakAnimated series | 2003 | 1 | 52 | Comedy | Mark Gravas |
| Baby Looney TunesAnimated series | 2002–2006 | 2 | 53 | Comedy | |
| Clone HighAnimated series | 2002–2003 | 3 | 33 | Animated sitcom | Phil Lord and Christopher Miller |
| Codename: Kids Next DoorAnimated series | 2002–2008 | 6 | 78 | Children's | Tom Warburton |
| CyberchaseAnimated series | 2002 | 16 | 153 | Educational | |
| He-Man and the Masters of the UniverseAnimated series | 2002–2004 | 2 | 39 | Comedy | Mattel |
| Megas XLRAnimated series | 2002–2005 | 2 | 26 | Children's | |
| Whatever Happened to... Robot Jones?Animated series | 2002–2003 | 2 | 13 | Comedy | Greg Miller |
| Grim & EvilAnimated series | 2001–2003 | 2 | 13 | Comedy | Maxwell Atoms |
| Justice LeagueAnimated series | 2001–2004 | 2 | 52 | Action | Bruce Timm |
| Sitting DucksAnimated series | 2001–2004 | 2 | 26 | Comedy | |
| The Cramp TwinsAnimated series | 2001–2006 | 2 | 52 | Comedy | Brian Wood |
| The Grim Adventures of Billy & MandyAnimated series | 2001–2007 | 7 | 78 | Children's | Maxwell Atoms |
| Time SquadAnimated series | 2001–2003 | 2 | 26 | Science fiction | Dave Wasson |
| UndergradsAnimated series | 2001 | 1 | 13 | College life | |
| Hot Wheels: World Race | 2000 | — | — | Fantasy | |
| Max SteelAnimated series | 2000–2002 | 3 | 36 | Science fiction | |
| Rainbow FishAnimated series | 2000 | 1 | 26 | Children's | |
| Sheep in the Big CityAnimated series | 2000–2002 | 2 | 26 | Alternative comedy | Mo Willems |
| The Brak ShowAnimated series | 2000–2003 | 3 | 30 | Black comedy | |
| WunschpunschAnimated series | 2000–2002 | 2 | 52 | Comedy | Michael Ende |
| Courage the Cowardly DogAnimated series | 1999–2002 | 4 | 52 | Slapstick | John R. Dilworth |
| Ed, Edd n EddyAnimated series | 1999–2009 | 6 | 69 | Comedy | Danny Antonucci |
| Mike, Lu & OgAnimated series | 1999–2001 | 2 | 26 | Comedy | Charles Swenson |
| The Tex Avery ShowAnimated series | 1999–2002 | — | 99 | Anthology | |
| Web Premiere ToonsWeb series | 1999–2001 | — | — | Anthology | |
| The Powerpuff GirlsAnimated series | 1998–2005 | 6 | 78 | Fantasy | Craig McCracken |
| Cartoon PlanetAnimated series | 1997–2014 | 3 | 146 | Comedy | Keith Crofford |
| I Am WeaselAnimated series | 1997–2000 | 5 | 79 | Comedy | David Feiss |
| Johnny BravoAnimated series | 1997–2004 | 4 | 65 | Animated sitcom | Van Partible |
| O Canada | 1997–2002 | — | — | Anthology | |
| Big Bag | 1996–1998 | 2 | 30 | Children's | Nina Elias-Bamberger |
| Cave KidsAnimated series | 1996 | 1 | 8 | Children's | |
| Dexter's LaboratoryAnimated series | 1996–2003 | 4 | 78 | Children's | Genndy Tartakovsky |
| The Real Adventures of Jonny QuestAnimated series | 1996–1997 | 2 | 52 | Fantasy | |
| Cow and ChickenAnimated series | 1995–1999 | 4 | 52 | Comedy | David Feiss |
| Mina and the CountAnimated series | 1995–1999 | 1 | 6 | — | Rob Renzetti |
| The Little Lulu ShowAnimated series | 1995–1999 | 3 | 52 | Comedy | |
| What a Cartoon!Animated series | 1995–1997 | — | 48 | Fantasy | Fred Seibert |
| Space Ghost Coast to CoastAnimated series | 1994–2008 | 11 | 113 | Talk show | Mike Lazzo |
| 2 Stupid DogsAnimated series | 1993–1995 | 2 | 39 | Comedy | Donovan Cook |
| The Moxy ShowAnimated series | 1993–1995 | — | 24 | Anthology | |
| ToonHeadsAnimated series | 1992–2003 | 3 | 82 | Anthology | |
| Hello Kitty's Furry Tale TheaterAnimated series | 1987 | 1 | 26 | Children's | |
| Where's Huddles?Animated series | 1970 | 1 | 10 | Animated sitcom | |
| Roger RamjetAnimated series | 1965 | 5 | 156 | — | Fred Crippen |
| Secret SquirrelAnimated series | 1965 | 2 | 39 | Comedy | |