| Regular Show: The Lost TapesAnimated series | Cartoon Network | 2026–on air | — | — | J. G. Quintel |
| Haha, You ClownsAnimated series | Adult Swim | 2025–on air | — | — | Joe Cappa |
| GrimsburgAnimated series | Fox | 2024–on air | 2 | 19 | |
| Hazbin HotelAnimated series | | 2024–on air | 2 | 16 | Vivienne Medrano |
| Koala ManAnimated series | Hulu | 2023–on air | 1 | 8 | Michael Cusack |
| KrapopolisAnimated series | Fox | 2023–on air | 3 | 58 | Dan Harmon |
| Royal CrackersAnimated series | Adult Swim | 2023–on air | 2 | 20 | Jason Ruiz |
| FairviewAnimated series | Comedy Central | 2022–on air | 1 | 8 | |
| FarzarAnimated series | Netflix | 2022–on air | 1 | 10 | Waco O'Guin, Roger Black |
| Human ResourcesAnimated series | Netflix | 2022–2023 | 2 | 20 | Nick Kroll |
| Smiling FriendsAnimated series | Adult Swim | 2022–2026 | 3 | 27 | Zach Hadel, Michael Cusack |
| BirdgirlAnimated series | Adult Swim | 2021–on air | 2 | 12 | Michael Ouweleen, Erik Richter |
| Chicago Party AuntAnimated series | Netflix | 2021–on air | — | 16 | Chris Witaske, Katie Rich |
| HouseBrokenAnimated series | Fox | 2021–2023 | 2 | 30 | Clea DuVall, Jennifer Crittenden |
| Santa Inc.Animated series | HBO Max | 2021–on air | — | — | |
| The Great NorthAnimated series | Fox | 2021–2025 | 5 | 97 | Molyneux sisters |
| The PrinceAnimated series | Hulu | 2021–on air | 1 | 12 | Gary Janetti |
| Close EnoughAnimated series | HBO Max | 2020–2022 | 3 | 24 | J. G. Quintel |
| Crossing SwordsAnimated series | Hulu | 2020–2021 | 2 | 20 | John Harvatine IV, Tom Root |
| DicktownAnimated series | FXX | 2020–2022 | 2 | — | David Rees, John Hodgman |
| DuncanvilleAnimated series | Fox | 2020–2022 | 3 | 39 | Amy Poehler, Julie Thacker |
| HoopsAnimated series | Netflix | 2020–on air | — | — | |
| Solar OppositesAnimated series | Hulu | 2020–2025 | 6 | 63 | Mike McMahan, Justin Roiland |
| Wild LifeAnimated series | Syfy | 2020 | — | — | |
| Bless the HartsAnimated series | Fox | 2019–2021 | 2 | 34 | Emily Spivey |
| Helluva BossAnimated web series | | 2019–on air | 3 | 21 | Vivienne Medrano |
| Tuca & BertieAnimated series | Netflix | 2019–2022 | 3 | 30 | Lisa Hanawalt |
| DisenchantmentAnimated series | Netflix | 2018–2023 | 3 | 50 | Matt Groening |
| Gary and His DemonsAnimated series | VRV, Mondo Media | 2018–on air | — | — | Mark Little |
| BordertownAnimated series | Fox | 2016 | 1 | 13 | |
| Camp WWEAnimated series | WWE Network | 2016–2018 | 2 | 10 | Seth Green |
| F Is for FamilyAnimated series | Netflix | 2015–2021 | 5 | 44 | Bill Burr, Michael Price |
| Moonbeam CityAnimated series | Comedy Central | 2015 | 1 | 10 | |
| BoJack HorsemanAnimated series | Netflix | 2014–2020 | 6 | 77 | Raphael Bob-Waksberg |
| ChozenAnimated series | FX | 2014 | 1 | 13 | |
| Long Live the RoyalsMiniseries | Cartoon Network | 2014–2015 | 1 | 4 | |
| Talking Tom and FriendsAnimated series | YouTube | 2014–2019 | 5 | 145 | |
| BrickleberryAnimated series | Comedy Central | 2012–2015 | 3 | 36 | |
| UnsupervisedAnimated series | FX | 2012 | 1 | 13 | David Hornsby |
| Allen GregoryAnimated series | Fox | 2011 | 1 | 7 | Jonah Hill |
| The Amazing World of GumballAnimated series | Cartoon Network | 2011–2019 | 7 | 240 | Ben Bocquelet |
| Neighbors from HellAnimated series | TBS | 2010 | 1 | 10 | Pam Brady |
| Glenn Martin, DDSAnimated series | Nick at Nite, Nickelodeon | 2009–2011 | 2 | 40 | |
| The Goode FamilyAnimated series | ABC | 2009 | 1 | 13 | Mike Judge |
| Click & Clack's As the Wrench TurnsAnimated series | PBS | 2008 | 1 | 10 | |
| The Life & Times of TimAnimated series | HBO | 2008–2012 | 3 | 30 | Steve Dildarian |
| Assy McGeeAnimated series | Cartoon Network, Adult Swim | 2006–2008 | 2 | 20 | Matt Harrigan |
| Squirrel BoyAnimated series | Cartoon Network | 2006–2007 | 2 | 52 | Everett Peck |
| Where My Dogs At?Animated series | MTV2 | 2006 | 1 | 8 | |
| American Dad!Animated series | TBS, Fox | 2005 | 22 | 399 | Seth MacFarlane, Matt Weitzman |
| House of CosbysAnimated series | Channel 101 | 2005 | 1 | 4 | Justin Roiland |
| Drawn TogetherAnimated series | Comedy Central | 2004–2007 | 3 | 36 | Dave Jeser & Matt Silverstein |
| Father of the PrideAnimated series | NBC | 2004–2005 | 1 | 15 | Jeffrey Katzenberg |
| FatherhoodAnimated series | Nick at Nite, Nickelodeon | 2004–2005 | 2 | 26 | Bill Cosby |
| Game OverAnimated series | UPN | 2004 | 1 | 6 | David Sacks |
| Maya & MiguelAnimated series | PBS, PBS Kids Go! | 2004–2007 | 5 | 65 | Deborah Forte |
| Free for AllAnimated series | Showtime | 2003 | 1 | 7 | |
| Gary the RatAnimated series | Spike TV | 2003 | 1 | 13 | Mark Cullen |
| Hey Monie!Animated series | Oxygen | 2003 | 3 | 25 | Dorothea Gillim |
| Kid NotoriousAnimated series | Comedy Central | 2003 | 2 | 9 | Brett Morgen |
| 3-SouthAnimated series | MTV | 2002–2003 | 1 | 13 | Mark Hentemann |
| Clone HighAnimated series | HBO Max, MTV | 2002–2003 | 3 | 33 | Phil Lord and Christopher Miller |
| Fillmore!Animated series | ABC, ABC Kids | 2002–2004 | 2 | 26 | Scott Gimple |
| Gary & MikeAnimated series | UPN | 2001 | 1 | 13 | |
| The OblongsAnimated series | The WB | 2001–2002 | 1 | 13 | Angus Oblong, Jace Richdale |
| The Proud FamilyAnimated series | Disney Channel | 2001–2005 | 3 | 52 | Bruce W. Smith |
| UndergradsAnimated series | Adult Swim, MTV2 | 2001 | 1 | 13 | |
| God, the Devil and BobAnimated series | NBC | 2000 | 1 | 13 | Matthew Carlson |
| Harvey Birdman, Attorney at LawAnimated series | Adult Swim | 2000–2007 | 4 | 39 | Michael Ouweleen |
| Teacher's PetAnimated series | ABC | 2000–2002 | 3 | 40 | Bill Steinkellner, Cheri Steinkellner |
| DowntownAnimated series | MTV, MTV2 | 1999 | 1 | 13 | Chris Prynoski |
| Home MoviesAnimated series | Adult Swim, UPN | 1999–2004 | 4 | 52 | Loren Bouchard, Brendon Small |
| Mission HillAnimated series | The WB | 1999–2002 | 1 | 13 | Josh Weinstein, Bill Oakley |
| SpongeBob SquarePantsAnimated series | Nickelodeon, ARB Günəş | 1999 | 16 | 330 | Stephen Hillenburg |
| Stressed EricAnimated series | BBC Two | 1998–2000 | 2 | 13 | |
| Johnny BravoAnimated series | Cartoon Network | 1997–2004 | 4 | 65 | Van Partible |
| King of the HillAnimated series | Adult Swim, Fox | 1997–2010 | 15 | 259 | Greg Daniels, Mike Judge |
| The Angry BeaversAnimated series | Nickelodeon | 1997–2001 | 4 | 64 | Mitch Schauer |
| Dr. Katz, Professional TherapistAnimated series | Comedy Central | 1995–1999 | 6 | 86 | Jonathan Katz, Tom Snyder |
| Timon & PumbaaAnimated series | CBS, Syndication | 1995–1999 | 3 | 85 | Disney Television Animation |
| DuckmanAnimated series | USA Network | 1994–1997 | 4 | 70 | Everett Peck |
| Capitol CrittersAnimated series | ABC | 1992 | 1 | 13 | Nat Mauldin |
| The SimpsonsAnimated series | Fox | 1989 | 38 | 813 | Matt Groening |
| The New Archies | NBC | 1987 | 1 | 14 | |
| The Addams FamilyAnimated series | NBC | 1973 | 1 | 16 | Charles Addams |
| The Roman HolidaysAnimated series | NBC | 1972 | — | 13 | |
| Where's Huddles?Animated series | CBS, Cartoon Network | 1970 | 1 | 10 | |