Cable channel · 2000–2009
Cartoon Network in the 2000s
72 shows premiered on Cartoon Network in the 2000s, in order of premiere.
| Premiere | Show | Years | Seasons | Episodes | Genre | Created by |
|---|---|---|---|---|---|---|
| — | Hot Wheels: World Race | 2000 | — | — | Fantasy | |
| Jan 8 | Rainbow FishAnimated series | 2000 | 1 | 26 | Children's | |
| Feb 26 | Max SteelAnimated series | 2000–2002 | 3 | 36 | Science fiction | |
| Oct 14 | WunschpunschAnimated series | 2000–2002 | 2 | 52 | Comedy | Michael Ende |
| Nov 17 | Sheep in the Big CityAnimated series | 2000–2002 | 2 | 26 | Alternative comedy | Mo Willems |
| Dec 21 | The Brak ShowAnimated series | 2000–2003 | 3 | 30 | Black comedy | |
| — | The Cramp TwinsAnimated series | 2001–2006 | 2 | 52 | Comedy | Brian Wood |
| Apr 1 | UndergradsAnimated series | 2001 | 1 | 13 | College life | |
| Jun 8 | Time SquadAnimated series | 2001–2003 | 2 | 26 | Science fiction | Dave Wasson |
| Aug 24 | Grim & EvilAnimated series | 2001–2003 | 2 | 13 | Comedy | Maxwell Atoms |
| Aug 24 | The Grim Adventures of Billy & MandyAnimated series | 2001–2007 | 7 | 78 | Children's | Maxwell Atoms |
| Sep 13 | Sitting DucksAnimated series | 2001–2004 | 2 | 26 | Comedy | |
| Nov 17 | Justice LeagueAnimated series | 2001–2004 | 2 | 52 | Action | Bruce Timm |
| — | Megas XLRAnimated series | 2002–2005 | 2 | 26 | Children's | |
| Jan 21 | CyberchaseAnimated series | 2002 | 16 | 153 | Educational | |
| Jul 12 | Whatever Happened to... Robot Jones?Animated series | 2002–2003 | 2 | 13 | Comedy | Greg Miller |
| Aug 16 | He-Man and the Masters of the UniverseAnimated series | 2002–2004 | 2 | 39 | Comedy | Mattel |
| Sep 7 | Baby Looney TunesAnimated series | 2002–2006 | 2 | 53 | Comedy | |
| Nov 2 | Clone HighAnimated series | 2002–2003 | 3 | 33 | Animated sitcom | Phil Lord and Christopher Miller |
| Dec 6 | Codename: Kids Next DoorAnimated series | 2002–2008 | 6 | 78 | Children's | Tom Warburton |
| Feb 16 | The Venture Bros.Animated series | 2003–2018 | 7 | 81 | Comedy | Doc Hammer, Christopher McCulloch |
| Jul 11 | Evil Con CarneAnimated series | 2003–2004 | 2 | 14 | Science fiction comedy | Maxwell Atoms |
| Jul 19 | Teen TitansAnimated series | 2003–2006 | 5 | 65 | Children's | Glen Murakami |
| Aug 23 | Duck DodgersAnimated series | 2003–2005 | 3 | 39 | Children's | |
| Nov 7 | Star WarsAnimated series | 2003–2005 | 3 | 25 | Fantasy | Genndy Tartakovsky |
| Nov 9 | Yakkity YakAnimated series | 2003 | 1 | 52 | Comedy | Mark Gravas |
| Jul 31 | Justice League UnlimitedAnimated series | 2004–2006 | 3 | 39 | Science fiction | Paul Dini |
| Aug 13 | Foster's Home for Imaginary FriendsAnimated series | 2004–2009 | 6 | 79 | Fantasy | Craig McCracken |
| Nov 14 | Tom Goes to the MayorAnimated series | 2004–2006 | 2 | 31 | Adult animation | Tim Heidecker |
| Nov 19 | Hi Hi Puffy AmiYumiAnimated series | 2004–2006 | 3 | 39 | Comedy anime and manga | Sam Register |
| Jan 23 | Pet AlienAnimated series | 2005 | 2 | 52 | Comedy | Jeff Muncy |
| Mar 25 | Krypto the SuperdogAnimated series | 2005–2006 | 2 | 39 | — | |
| May 30 | The Life & Times of Juniper LeeAnimated series | 2005–2007 | 3 | 40 | Action | Judd Winick |
| Jun 19 | 12 oz. MouseAnimated series | 2005–2018 | 3 | 22 | Exploitation | Matt Maiellaro |
| Jul 8 | Camp LazloAnimated series | 2005–2008 | 5 | 61 | Children's | Joe Murray |
| Aug 22 | Firehouse TalesAnimated series | 2005–2006 | 1 | 26 | Children's | |
| Aug 22 | Gerald McBoing-Boing | 2005–2007 | 1 | 52 | — | Dr. Seuss |
| Sep 17 | Johnny TestAnimated series | 2005–2014 | 6 | 117 | Children's | Scott Fellows |
| Oct 2 | Sunday Pants | 2005 | 1 | 7 | — | |
| Oct 30 | Lucy, the Daughter of the DevilAnimated series | 2005–2007 | 1 | 11 | Adult animation | Loren Bouchard |
| Dec 26 | My Gym Partner's a MonkeyAnimated series | 2005–2008 | 4 | 52 | Children's | Julie McNally-Cahill |
| Dec 27 | Ben 10Animated series | 2005–2008 | 4 | 52 | Fantasy | Man of Action Studios |
| May 27 | Squirrel BoyAnimated series | 2006–2007 | 2 | 52 | Animated sitcom | Everett Peck |
| Aug 6 | MetalocalypseAnimated series | 2006–2013 | 4 | 63 | Music | Tommy Blacha, Brendon Small |
| Sep 2 | Fantastic Four: World's Greatest HeroesAnimated series | 2006–2007 | 1 | 26 | Action | |
| Sep 29 | Ellen's Acres | 2006–2007 | — | 52 | — | Larry Schwarz |
| Nov 3 | Class of 3000Animated series | 2006–2008 | 2 | 28 | — | |
| Nov 26 | Assy McGeeAnimated series | 2006–2008 | 2 | 20 | Detective | Matt Harrigan |
| Feb 11 | Tim and Eric Awesome Show, Great Job! | 2007–2010 | 5 | 50 | Sketch comedy | Tim Heidecker |
| Mar 4 | The Land Before TimeAnimated series | 2007–2008 | 1 | 26 | Comedy | Tony Geiss, Charles Grosvenor |
| May 25 | Storm HawksAnimated series | 2007–2009 | 2 | 52 | Science fiction | Asaph Fipke |
| Jun 17 | The Othersiders | 2007–2009 | 2 | 23 | — | |
| Jun 29 | George of the JungleAnimated series | 2007–2017 | 2 | 52 | Comedy | Jay Ward |
| Jul 10 | Rick & Steve: The Happiest Gay Couple in All the WorldAnimated series | 2007–2009 | 2 | 14 | Brickfilm | Q. Allan Brocka |
| Nov 2 | ChowderAnimated series | 2007–2010 | 3 | 49 | Fantasy | C. H. Greenblatt |
| Nov 4 | Xavier: Renegade AngelAnimated series | 2007–2009 | 2 | 20 | Adult animation | Vernon Chatman, John Lee |
| Dec 26 | Transformers: AnimatedAnimated series | 2007–2009 | 3 | 42 | Science fiction | Hasbro |
| Feb 15 | TWF - Thumb Wrestling Federation | 2008–2009 | 5 | 92 | Parody | Larry Schwarz |
| Apr 18 | Ben 10: Alien ForceAnimated series | 2008–2010 | 3 | 46 | Children's | Man of Action Studios |
| Jun 5 | The Marvelous Misadventures of FlapjackAnimated series | 2008–2010 | 3 | 46 | Children's | Thurop Van Orman |
| Sep 7 | Hole in the Wall | 2008–2009 | — | — | Game show | |
| Oct 3 | Star WarsAnimated series | 2008–2020 | 7 | 133 | Fantasy | George Lucas |
| Oct 3 | The Secret SaturdaysAnimated series | 2008–2010 | 2 | 36 | Adventure | Jay Stephens |
| Nov 14 | Batman: The Brave and the BoldAnimated series | 2008–2011 | 3 | 65 | Fantasy | |
| Jun 20 | BrainRush | 2009 | 1 | 6 | — | |
| Jun 20 | Destroy Build Destroy | 2009–2011 | 4 | 37 | — | |
| Aug 19 | Bobb'e Says | 2009 | 1 | 6 | — | |
| Aug 19 | Dude, What Would Happen | 2009–2011 | 4 | 37 | — | |
| Aug 29 | Hot Wheels: Battle Force 5Animated series | 2009–2011 | 3 | 54 | Comedy | |
| Sep 14 | The Super Hero Squad ShowAnimated series | 2009–2011 | 2 | 52 | Comedy | Stan Lee |
| Sep 27 | Titan MaximumAnimated series | 2009 | — | 72 | — | Matthew Senreich |
| Oct 5 | Casper's Scare SchoolAnimated series | 2009–2012 | 3 | 54 | Comedy |