| Phoebe & JayAnimated series | 2026–on air | 1 | 10 | — | |
| Skillsville | 2025–2026 | — | — | — | |
| Donkey Hodie | 2021–on air | — | — | Children's | |
| Elinor Wonders WhyAnimated series | 2020–on air | — | 40 | Educational | Jorge Cham |
| Hero ElementaryAnimated series | 2020–2022 | — | — | Children's | Christine Ferraro, Carol-Lynn Parente |
| Clifford the Big Red Dog | 2019–2021 | 1 | 36 | — | |
| Molly of DenaliAnimated series | 2019–on air | 4 | 67 | Children's | |
| Xavier Riddle and the Secret MuseumAnimated series | 2019–on air | 2 | 47 | Comedy | |
| Esme & RoyAnimated series | 2018–2021 | 2 | 52 | Children's | |
| Let's Go Luna!Animated series | 2018–2020 | 2 | 64 | Comedy | Joe Murray |
| Pinkalicious & PeterrificAnimated series | 2018–2025 | 7 | 81 | Children's | |
| Ready Jet Go!Animated series | 2016–2019 | 2 | 64 | Fantasy | |
| Splash and BubblesAnimated series | 2016–2018 | 1 | 40 | Fantasy | John Tartaglia |
| Nature CatAnimated series | 2015–2024 | 5 | 91 | Children's | |
| Odd Squad | 2014–2022 | 3 | 108 | Educational entertainment | Adam Peltzman, Tim McKeon |
| Peg + CatAnimated series | 2013–2018 | 2 | 63 | Children's | |
| Daniel Tiger's NeighborhoodAnimated series | 2012 | 6 | 139 | Comedy | Angela Santomero |
| Dinosaur TrainAnimated series | 2009–2020 | 5 | 100 | Fantasy | Craig Bartlett |
| Martha SpeaksAnimated series | 2008–2014 | 6 | 96 | Comedy | Susan Meddaugh |
| Sid The Science KidAnimated series | 2008–2013 | 2 | 54 | Children's | Jim Henson |
| biz KID$ | 2008–2017 | 5 | 65 | — | |
| Super Why!Animated series | 2007–2016 | 3 | 103 | Music | Angela Santomero |
| WordGirlAnimated series | 2007–2015 | 8 | 130 | Comedy | |
| Curious GeorgeAnimated series | 2006–2022 | 15 | 198 | Comedy | Margret Rey |
| It's a Big Big World | 2006–2010 | 2 | 47 | — | Mitchell Kriegman |
| SeeMore's Playhouse | 2006–2012 | 2 | 30 | — | |
| Peep and the Big Wide WorldAnimated series | 2004–2011 | 5 | 55 | Comedy | |
| Clifford's Puppy Days | 2003–2006 | 3 | 63 | — | Norman Bridwell |
| Jakers! The Adventures of Piggley WinksAnimated series | 2003–2007 | 3 | 52 | — | Mike Young |
| CyberchaseAnimated series | 2002 | 16 | 153 | Educational | |
| DragonflyTV | 2002–2008 | 7 | 72 | — | Minnesota PBS |
| Make Way for NoddyAnimated series | 2002–2007 | 2 | 100 | Comedy | Enid Blyton |
| Sagwa the Chinese Siamese CatAnimated series | 2001–2002 | 1 | 40 | Children's | Amy Tan |
| Between the Lions | 2000–2010 | 10 | 130 | Children's | |
| Clifford the Big Red DogAnimated series | 2000–2003 | 2 | 65 | Fantasy | |
| Timothy Goes to School | 2000–2001 | 2 | 26 | Animation | Rosemary Wells |
| Dragon TalesAnimated series | 1999–2005 | 3 | 93 | Children's | Ron Rodecker |
| Zoboomafoo | 1999–2001 | 2 | 65 | Live action & animation | Martin Kratt |
| St. Bear's Dolls Hospital | 1998 | — | — | Children's | |
| Adventures from the Book of VirtuesAnimated series | 1996–2000 | 3 | 39 | Children's | |
| Kratts' Creatures | 1996 | 1 | 50 | — | Martin Kratt, Chris Kratt |
| Jay Jay the Jet Plane | 1994–2005 | 4 | 62 | Children's | |