| Premiere | Show | Years | Seasons | Episodes | Genre | Created by |
|---|---|---|---|---|---|---|
| Feb 14 | The Young TurksNews program | 2002 | 13 | — | Talk show | Cenk Uygur |
| Mar 26 | The Angry Video Game NerdWeb series | 2006 | 16 | 201 | Comedy | James Rolfe |
| Jun 3 | Animator vs. AnimationAnimated series | 2006 | 3 | — | Comedy | Alan Becker |
| Jun 16 | lonelygirl15Web series | 2006–2008 | 3 | 547 | — | Mesh Flinders |
| Nov 29 | The Temp LifeWeb series | 2006–2011 | 5 | 43 | Comedy | Wilson Cleveland |
| — | Meet The TeamMiniseries | 2007–2012 | — | 10 | Machinima | Valve Corporation |
| Jun 27 | The GuildWeb series | 2007–2013 | 6 | 70 | Comedy | Felicia Day |
| Jul 3 | Nostalgia CriticWeb series | 2007 | 10 | 561 | Review | |
| Sep 10 | Seth MacFarlane's Cavalcade of Cartoon ComedyAnimated web series | 2008–2009 | 1 | 50 | Comedy | Seth MacFarlane |
| Jun 20 | Marble HornetsWeb series | 2009–2014 | 3 | 130 | Found footage | |
| Oct 9 | Annoying OrangeWeb series | 2009 | 18 | 852 | Comedy | Dane Boedigheimer |