| Premiere | Show | Years | Seasons | Episodes | Genre | Created by |
|---|---|---|---|---|---|---|
| Apr 15 | ¡Qué Locuras! | 2000 | — | — | Hidden camera | |
| Jan 10 | Trato Hecho | 2005 | — | — | Game show | Monty Hall |
| May 23 | Soñar no Cuesta Nada | 2005–2006 | — | 191 | Telenovela | |
| Mar 27 | Nuestra Belleza Latina | 2007 | 11 | 110 | Reality | |
| Mar 27 | Nuestra Belleza Latina 2007 | 2007 | — | 11 | — | |
| Oct 30 | Como Ama una MujerMiniseries | 2007 | — | 5 | Drama | Jennifer Lopez |
| Jan 10 | Desperate Housewives | 2008 | 1 | 24 | Soap opera | Marc Cherry |
| Jan 21 | Amor Comprado | 2008 | — | 123 | Telenovela | |
| Mar 10 | Valeria | 2008 | 1 | 174 | Telenovela | Alberto Gómez |
| Aug 10 | Pecadora | 2009–2010 | — | 80 | Telenovela | |
| Aug 30 | ¡Viva el Sueño! | 2009 | 1 | — | Reality |