| Premiere | Show | Years | Seasons | Episodes | Genre | Created by |
|---|---|---|---|---|---|---|
| Aug 16 | Hardcore Pawn | 2010–2015 | 9 | 162 | Reality | |
| Jun 22 | The Chris Gethard Show | 2011–2018 | — | 201 | Variety show | Chris Gethard |
| Jul 20 | South Beach Tow | 2011–2014 | 4 | 86 | Reality | Jennifer Lopez |
| Dec 15 | Impractical Jokers | 2011 | 12 | 287 | Comedy | |
| Nov 23 | Killer Karaoke | 2012–2014 | 2 | 16 | Game show | |
| Jan 1 | Hardcore Pawn: Chicago | 2013 | 1 | 18 | Reality | |
| Feb 7 | Guinness World Records Gone Wild | 2013–2014 | 2 | 8 | Reality | |
| Apr 1 | The Carbonaro Effect | 2014 | 3 | 40 | — | |
| Jan 6 | Hack My Life | 2015–2018 | 2 | 30 | — | |
| Sep 29 | Adam Ruins Everything | 2015–2019 | 2 | 42 | Sketch comedy | Adam Conover |
| Feb 11 | Those Who Can't | 2016–2019 | 1 | 10 | — | |
| Apr 21 | Comedy Knockout | 2016–2018 | — | 58 | — | |
| Apr 5 | Talk Show The Game Show | 2017 | 2 | 32 | Talk show | Guy Branum |
| Jul 12 | I'm Sorry | 2017 | 2 | 20 | Comedy | |
| Oct 24 | At Home with Amy Sedaris | 2017–2020 | 3 | 16 | Surreal humour | |
| Jan 3 | Laff Mobb's Laff Tracks | 2018–on air | 2 | 38 | Comedy | |
| Jul 11 | Bobcat Goldthwait's Misfits & Monsters | 2018 | 1 | 8 | — | |
| Mar 28 | Tacoma FD | 2019–2023 | 4 | 49 | Comedy |