| Premiere | Show | Years | Seasons | Episodes | Genre | Created by |
|---|---|---|---|---|---|---|
| — | Mystery! | 1980–2006 | 27 | 648 | Anthology | |
| Jan 14 | 3-2-1 Contact | 1980–1988 | 7 | 225 | — | |
| Sep 28 | Cosmos | 1980 | 1 | 13 | Popularisation of science | Carl Sagan, Steven Soter |
| Oct 2 | From Jump Street: The Story of Black Music | 1980 | — | 13 | Documentary | |
| Oct 5 | Up and Coming | 1980–1981 | 1 | 2 | — | |
| — | Wild America | 1982–1994 | 12 | 120 | Nature documentary | |
| Jan 12 | American Playhouse | 1982–1993 | 13 | 182 | Anthology | |
| Oct 10 | Nature | 1982 | 36 | 521 | Documentary | Thomas E. Lovejoy, George Page |
| Dec 12 | Powerhouse | 1982–1983 | 1 | 16 | — | |
| — | Computer Chronicles | 1983–2002 | — | — | Current affairs | Stewart Cheifet |
| Jan 11 | The Joy of Painting | 1983–1994 | 31 | 403 | — | Bob Ross |
| Jan 17 | FrontlineWeb series | 1983 | 42 | 775 | Documentary | David Fanning |
| Jun 6 | Reading Rainbow | 1983–2006 | 15 | 150 | — | |
| Oct 2 | Don't Look Now | 1983 | 1 | 5 | — | |
| — | The Voyage of the Mimi | 1984 | — | 13 | Educational | Bank Street College of Education |
| — | The Mechanical Universe | 1985–1986 | 1 | 52 | Documentary | |
| Jun 22 | American Masters | 1986 | 35 | — | Biography | |
| Nov 1 | Hometime | 1986–2016 | 29 | — | — | Dean Johnson |
| — | French in Action | 1987 | — | 52 | — | Pierre Capretz |
| — | Trying Times | 1987–1989 | — | — | Comedy | |
| Jan 21 | Eyes on the Prize | 1987–1990 | 2 | 14 | Documentary | |
| Jan 26 | Mathnet | 1987–1992 | 5 | 30 | Police procedural | |
| Jan 26 | Square One Television | 1987–1992 | — | 230 | — | |
| Aug 31 | Learn to Read | 1987 | 1 | 30 | — | |
| — | Project Mathematics! | 1988–2000 | 1 | 9 | Documentary | |
| Feb 15 | Gerbert | 1988–1991 | 3 | 50 | — | |
| Jun 21 | The Power of Myth | 1988 | — | 6 | Documentary | |
| Jul 5 | Point of View | 1988 | 34 | 224 | Documentary | |
| Oct 4 | American Experience | 1988 | 30 | 313 | Documentary | |
| Jan 7 | The New Yankee Workshop | 1989 | — | 284 | — | Russell Morash |
| Jan 29 | Shining Time Station | 1989–1993 | 3 | 75 | Anthology | Britt Allcroft |