| Premiere | Show | Years | Seasons | Episodes | Genre | Created by |
|---|---|---|---|---|---|---|
| Feb 23 | WWE NXT | 2010 | 12 | 777 | Reality | Vince McMahon, Triple H |
| Mar 28 | The Confession | 2011 | 1 | 10 | Drama | Kiefer Sutherland |
| Aug 17 | A Day in the Life | 2011–2012 | 2 | 16 | — | |
| Feb 14 | Battleground | 2012 | 1 | 13 | Comedy-drama | |
| Sep 25 | The Mindy Project | 2012–2017 | 6 | 117 | Sitcom | Mindy Kaling |
| Feb 25 | Raising the Bar | 2013 | 1 | 6 | — | |
| Jun 3 | East Los High | 2013–2017 | 3 | 48 | Teen drama | |
| Aug 5 | Quick Draw | 2013–2014 | 2 | 18 | Comedy | |
| Nov 6 | Mother Up! | 2013–2014 | 1 | 13 | — | |
| Apr 9 | Deadbeat | 2014–2016 | 3 | 36 | Comedy | |
| Apr 25 | The DoozersAnimated series | 2014–2018 | 1 | 52 | — | |
| Jul 15 | The Hotwives | 2014–2015 | 2 | 14 | Sitcom | Danielle Schneider, Dannah Phirman |
| Sep 30 | Selfie | 2014 | 1 | 13 | Sitcom | Emily Kapnek |
| Apr 9 | Resident Advisors | 2015 | 1 | 7 | Comedy | |
| Oct 7 | Casual | 2015–2018 | 4 | 44 | Comedy-drama | |
| Feb 15 | 11.22.63Miniseries | 2016 | 1 | 8 | Thriller | |
| Mar 30 | The Path | 2016–2018 | 3 | 36 | Drama | |
| Oct 10 | Freakish | 2016–2017 | 1 | 10 | Horror | |
| Oct 19 | Chance | 2016–2017 | 2 | 20 | — | Kem Nunn |
| Dec 7 | Shut Eye | 2016–2017 | 2 | 20 | Drama | |
| Apr 4 | Dimension 404 | 2017 | 1 | 6 | Black comedy | |
| Apr 26 | The Handmaid’s Tale | 2017–2025 | 6 | 66 | Post-apocalyptic | Bruce Miller |
| Sep 10 | The Orville | 2017 | 3 | 36 | Science fiction | Seth MacFarlane |
| Oct 12 | I Love You, America with Sarah Silverman | 2017–2018 | 1 | 5 | Talk show | |
| Nov 14 | Future Man | 2017–2020 | 3 | 34 | Science fiction | Kyle Hunter, Howard Overman |
| Nov 21 | Runaways | 2017–2019 | 3 | 33 | Fantasy | Josh Schwartz |
| Feb 28 | The Looming TowerMiniseries | 2018 | 1 | 10 | Drama | Dan Futterman |
| May 11 | All Night | 2018–on air | 1 | 10 | — | |
| Jul 25 | Castle RockWeb series | 2018–2019 | 2 | 20 | Horror | Dustin Thomason |
| Sep 14 | The First | 2018 | 1 | 8 | Science fiction | Beau Willimon |
| Oct 5 | Into the Dark | 2018–2021 | 2 | 24 | Horror | |
| Oct 12 | Light as a Feather | 2018–2019 | 2 | 26 | Thriller | |
| Nov 16 | Holly Hobbie | 2018–2022 | — | — | Musical | |
| Feb 8 | PEN15 | 2019–2021 | 2 | 25 | Comedy | Sam Zvibleman, Maya Erskine |
| Mar 15 | Shrill | 2019–on air | 3 | 22 | LGBTQ | |
| Mar 20 | The Act | 2019 | 1 | 8 | Drama | |
| Apr 19 | Ramy | 2019–on air | 3 | 30 | Comedy-drama | Ramy Youssef |
| May 17 | Catch-22 | 2019–on air | 1 | 6 | War | |
| Jun 21 | The Bravest KnightAnimated series | 2019 | 1 | 13 | — | |
| Jul 31 | Four Weddings and a FuneralMiniseries | 2019 | 1 | 10 | Romantic comedy | |
| Oct 18 | Looking for AlaskaMiniseries | 2019 | 1 | 8 | Teen drama | |
| Nov 15 | Dollface | 2019–2022 | 2 | 20 | Comedy | |
| Dec 6 | Reprisal | 2019–on air | 1 | 10 | — |