| Premiere | Show | Years | Seasons | Episodes | Genre | Created by |
|---|---|---|---|---|---|---|
| May 5 | Strike Back | 2010–2020 | 8 | 76 | Action | |
| May 13 | Femme Fatales | 2011–2012 | 2 | 28 | Anthology | |
| Aug 19 | Chemistry | 2011 | 1 | 13 | Comedy | |
| Feb 24 | The Girl's Guide to Depravity | 2012–2013 | 2 | 26 | — | |
| Jan 11 | Banshee | 2013–2016 | 4 | 38 | Drama | Jonathan Tropper |
| Mar 29 | Zane’s The Jump Off | 2013 | 1 | 13 | — | |
| Aug 8 | The Knick | 2014–2015 | 2 | 20 | Period drama | |
| Jun 3 | Outcast | 2016–2018 | 2 | 20 | Horror | Robert Kirkman |
| Sep 9 | QuarryMiniseries | 2016 | 1 | 8 | Drama | |
| Sep 22 | Mike Judge Presents: Tales from the Tour BusAnimated series | 2017 | 2 | 16 | — | Rich Mullins, Mike Judge |
| Jan 24 | The Other Two | 2019–on air | 3 | 30 | LGBTQ | Chris Kelly, Sarah Schneider |
| Apr 5 | Warrior | 2019–2023 | 3 | 30 | Drama | Jonathan Tropper, Justin Lin |
| Jun 14 | Jett | 2019 | 1 | 9 | Drama | |
| Jul 24 | South Side | 2019–2022 | — | — | Sitcom | Bashir Salahuddin |
| Jul 28 | Pennyworth | 2019–2022 | 3 | 30 | Alternate history |